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Chelation (/ k iː ˈ l eɪ ʃ ən /) is a type of bonding of ions and their molecules to metal ions. It involves the formation or presence of two or more separate coordinate bonds between a polydentate (multiple bonded) ligand and a single central metal atom.
DOTA is derived from the macrocycle known as cyclen.The four secondary amine groups are modified by replacement of the N-H centers with N-CH 2 CO 2 H groups. The resulting aminopolycarboxylic acid, upon ionization of the carboxylic acid groups, is a high affinity chelating agent for di- and trivalent cations.
DOTA (chelator) derivatives (6 P) S. Sequestrants (1 P) Siderophores (23 P) Pages in category "Chelating agents" The following 164 pages are in this category, out of ...
Chelating resins are a class of ion-exchange resins.They are almost always used to bind cations, and utilize chelating agents covalently attached to a polymer matrix. Chelating resins have the same bead form and polymer matrix as usual ion excha
EDDHA or ethylenediamine-N,N ′-bis(2-hydroxyphenylacetic acid) is a chelating agent.Like EDTA, it binds metal ions as a hexadentate ligand, using two amines, two phenolate centers, and two carboxylates as the six binding sites.
However, from a more comprehensive and chemistry point of view, they should be described as inert metals. Inert metals are very stable. They are difficult to participate directly in ordinary acid-base reactions and turn into metal compounds. Therefore, they can stay alone in the form of single element in nature.
TPEN (N,N,N ′,N ′-tetrakis(2-pyridinylmethyl)-1,2-ethanediamine [1]) is an intracellular membrane-permeable ion chelator. [2] TPEN has a high affinity for many transition metals and should not be considered specific or selective for a particular ion. Chelators can be used in chelation therapy to remove toxic metals in the body. TPEN is a ...
DOTAM (also known as TCMC) is an organic compound used as a chelator much like its carboxylic acid analog DOTA. A derivative with a reactive linking group of para-isothiocyanatobenzyl attached to the cyclen ring is also of interest as a bifunctional chelator (BFC).