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History of aspirin. Aspirin (acetylsalicylic acid), an organic compound that does not occur in nature, was first synthesised in 1899. In 1897, scientists at the drug and dye firm Bayer began investigating acetylated organic compounds as possible new medicines, following the success of acetanilide ten years earlier.
Aspirin is not recommended in the last part of pregnancy. [10] It is not generally recommended in children with infections because of the risk of Reye syndrome. [10] High doses may result in ringing in the ears. [10] A precursor to aspirin found in the bark of the willow tree (genus Salix) has been used for its health effects for at least 2,400 ...
Felix Hoffmann (21 January 1868 – 8 February 1946) was a German chemist notable for re-synthesising diamorphine (independently from C.R. Alder Wright who synthesized it 23 years earlier), which was popularized under the Bayer trade name of "heroin". He is also credited with synthesizing aspirin, though whether he did this under his own ...
A new DNA test suggests they might have even self-prescribed an early version of a common modern day painkiller.
Edward Stone was born in Princes Risborough, Buckinghamshire, England, in 1702. His parents were Edward Stone, a gentleman farmer, and his first wife Elizabeth Reynolds. His mother having died, his father took a second wife, Elizabeth Grubb, in 1707; the Grubb family was to play a major role in Stone's life. [ 1]
The therapeutic effects of salicylic acids were first documented in 1763 by Edward Stone, with acetylsalicylic acid being synthesized by Felix Hoffmann, a chemist working under Bayer, in 1897. [4] Acetylsalicylic acid-derived salt compounds were first discovered in 1970, [5] and the synthesis of lysine acetylsalicylate was first documented in ...
Asthma is a long-term inflammatory disease of the airways of the lungs. [4] It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. [9][10] Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. [3]
Additionally, aspirin induces the formation of NO-radicals in the body, which have been shown in mice to have an independent mechanism of reducing inflammation. This reduces leukocyte adhesion, which is an important step in immune response to infection. There is currently insufficient evidence to show that aspirin helps to fight infection. [17]