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The term variant of concern (VOC) for SARS-CoV-2, which causes COVID-19, is a category used for variants of the virus where mutations in their spike protein receptor binding domain (RBD) substantially increase binding affinity (e.g., N501Y) in RBD-hACE2 complex (genetic data), while also being linked to rapid spread in human populations ...
SARS‑CoV‑2 is a strain of the species Betacoronavirus pandemicum (SARSr-CoV), as is SARS-CoV-1, the virus that caused the 2002–2004 SARS outbreak. [ 2 ] [ 17 ] There are animal-borne coronavirus strains more closely related to SARS-CoV-2, the most closely known relative being the BANAL-52 bat coronavirus.
The Delta variant (B.1.617.2) was [3] [4] a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in India on 5 October 2020. It was first detected in India on 5 October 2020. The Delta variant was named on 31 May 2021 and had spread to over 179 countries by 22 November 2021.
On 26 November 2021, the WHO's Technical Advisory Group on SARS-CoV-2 Virus Evolution declared PANGO lineage B.1.1.529 a variant of concern and designated it with the Greek letter omicron. [10] The WHO skipped the preceding letters nu and xi in the Greek alphabet to avoid confusion with the similarities of the English word "new" and the Chinese ...
The many thousands of SARS-CoV-2 variants are grouped into either clades or lineages. [111] [112] The WHO, in collaboration with partners, expert networks, national authorities, institutions and researchers, have established nomenclature systems for naming and tracking SARS-CoV-2 genetic lineages by GISAID, Nextstrain and Pango.
The Beta variant, [1] [2] (B.1.351), [a] was [5] [6] a variant of SARS-CoV-2, the virus that causes COVID-19. One of several SARS-CoV-2 variants initially believed to be of particular importance , it was first detected in the Nelson Mandela Bay [ 7 ] metropolitan area of the Eastern Cape province of South Africa in October 2020, [ 8 ] which was ...
A UK case-control study for 54,906 participants, testing positive for SARS-CoV-2 between 1 October 2020 and 29 January 2021 in the community setting (not including vulnerable persons from care centres and other public institutions), reported that patients infected with the Alpha variant (VOC 202012/1) had a hazard ratio for death within 28 days ...
The Lambda variant, also known as lineage C.37, is a variant of SARS-CoV-2, the virus that causes COVID-19. [1] It was first detected in Peru in August 2020. [ 2 ] On 14 June 2021, the World Health Organization (WHO) named it Lambda variant [ 1 ] and designated it as a variant of interest . [ 3 ]