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A431 cells were established from an epidermoid carcinoma in the skin of an 85- year-old female patient. Epidermal growth factor (EGF) stimulation of A431 cells induces rapid tyrosine phosphorylation of intracellular signaling proteins which control cellular processes such as growth, proliferation and apoptosis.
These downstream signaling proteins initiate several signal transduction cascades, principally the MAPK, Akt and JNK pathways, leading to DNA synthesis and cell proliferation. [12] Such proteins modulate phenotypes such as cell migration, adhesion, and proliferation. Activation of the receptor is important for the innate immune response in ...
The origins of some immortal cell lines – for example, HeLa human cells – are from naturally occurring cancers. HeLa, the first immortal human cell line on record to be successfully isolated and proliferated by a laboratory, was taken from Henrietta Lacks in 1951 at Johns Hopkins Hospital in Baltimore, Maryland. [1]
Human protein-coding gene pages: •Python code for maintaining the list •List of human protein-coding genes page 1 covers genes A1BG–EPGN •List of human protein-coding genes page 2 covers genes EPHA1–MTMR3 •List of human protein-coding genes page 3 covers genes MTMR4–SLC17A7
Epithelial cell adhesion molecule (EpCAM), also known as CD326 among other names, is a transmembrane glycoprotein mediating Ca 2+-independent homotypic cell–cell adhesion in epithelia. [5] EpCAM is also involved in cell signaling, [ 6 ] migration, [ 7 ] proliferation, and differentiation. [ 8 ]
A431 may refer to: A431 road (England), a road between Bath and Bristol; A431 cells, an experimental cell line used in biomedical research
For example, researchers acknowledge that the short time frame may have been inadequate to evaluate the long-term effects of plant-based meat alternatives on other risk factors, such as blood sugar.
72962 Ensembl ENSG00000025708 ENSMUSG00000022615 UniProt P19971 Q99N42 RefSeq (mRNA) NM_001953 NM_001113755 NM_001113756 NM_001257988 NM_001257989 NM_138302 NM_028405 RefSeq (protein) NP_001107227 NP_001107228 NP_001244917 NP_001244918 NP_001944 NP_612175 Location (UCSC) Chr 22: 50.53 – 50.53 Mb Chr 15: 89.26 – 89.26 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse TYMP is a gene ...