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The laboratory mouse has been instrumental in investigating the genetics of human disease, including cancer, for over 110 years. [1] The laboratory mouse has physiology and genetic characteristics very similar to humans providing powerful models for investigation of the genetic characteristics of disease.
Mouse Genome Informatics (MGI) is a free, online database and bioinformatics resource hosted by The Jackson Laboratory, with funding by the National Human Genome Research Institute (NHGRI), the National Cancer Institute (NCI), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). [1]
The laboratory also provides more than 13,000 strains of mouse models to more than 2,400 organizations in 68 countries around the world. [1] Additionally, JAX is the home of the Mouse Genome Informatics database, and an international hub for scientific courses, conferences, training and education. [7]
The NSG mouse (NOD scid gamma mouse) is a brand of immunodeficient laboratory mice, developed and marketed by Jackson Laboratory, which carries the strain NOD.Cg-Prkdc scid Il2rg tm1Wjl /SzJ. NSG branded mice are among the most immunodeficient described to date. [1] NSG branded mice lack mature T cells, B cells, and natural killer (NK) cells. [2]
The MOuse NOnCode Lung database provides the annotations and expression profiles of mouse long non-coding RNAs (lncRNAs) involved in influenza and SARS-CoV infections. [9] NONCODE: An integrated knowledge database dedicated to ncRNAs, especially lncRNAs [10] lncRNome
Persson's most popular creation is the survival sandbox game Minecraft, which was first publicly available on 17 May 2009 [37] and fully released on 18 November 2011. Persson left his job as a game developer to work on Minecraft full-time until completion. In early 2011, Mojang AB sold the one millionth copy of the game, several months later ...
The Mouse Phenome Database (MPD) is a web-accessible database of strain characterization data for the laboratory mouse, to facilitate translational research for human health and disease. MPD characterizes phenotype as well as genotype , and provides tools for online analysis.
BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation.