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  2. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    The area under the effect curve (AUEC) is an integral of the effect of a drug over time, estimated as a previously-established function of concentration. It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing schedule variations than AUC.

  3. Carboplatin - Wikipedia

    en.wikipedia.org/wiki/Carboplatin

    Calvert formula: () = (+) The typical area under the curve (AUC) for carboplatin ranges from 3-7 (mg/ml)*min. [14] GFR (Glomerular Filtration Rate) is a measure or estimate of kidney function. This is either measured, by measuring clearance of a radioisotope or estimated using serum and (sometimes) urine creatine measurements.

  4. Bioavailability - Wikipedia

    en.wikipedia.org/wiki/Bioavailability

    The absolute bioavailability is the dose-corrected area under curve (AUC) non-intravenous divided by AUC intravenous. The formula for calculating the absolute bioavailability, F, of a drug administered orally (po) is given below (where D is dose administered).

  5. Receiver operating characteristic - Wikipedia

    en.wikipedia.org/wiki/Receiver_operating...

    The main criticism to the ROC curve described in these studies regards the incorporation of areas with low sensitivity and low specificity (both lower than 0.5) for the calculation of the total area under the curve (AUC)., [19] as described in the plot on the right.

  6. Receiver Operating Characteristic Curve Explorer and Tester

    en.wikipedia.org/wiki/Receiver_Operating...

    The AUC (area under the curve) of the ROC curve reflects the overall accuracy and the separation performance of the biomarker (or biomarkers), [3] and can be readily used to compare different biomarker combinations or models. [4] As a rule of thumb, the fewer the biomarkers that one uses to maximize the AUC of the ROC curve, the better.

  7. Mann–Whitney U test - Wikipedia

    en.wikipedia.org/wiki/Mann–Whitney_U_test

    The U statistic is related to the area under the receiver operating characteristic curve : [8] A U C 1 = U 1 n 1 n 2 {\displaystyle \mathrm {AUC} _{1}={U_{1} \over n_{1}n_{2}}} Note that this is the same definition as the common language effect size , i.e. the probability that a classifier will rank a randomly chosen instance from the first ...

  8. AUC - Wikipedia

    en.wikipedia.org/wiki/AUC

    Area under the curve (receiver operating characteristic), a performance measure for binary classifiers; Area under the curve (pharmacokinetics), regarding plasma drug concentration-time curves; Authentication Center in a GSM mobile phone network

  9. Area-under-the-curve - Wikipedia

    en.wikipedia.org/?title=Area-under-the-curve&...

    Download as PDF; Printable version; In other projects Appearance. move to sidebar hide. From Wikipedia, the free encyclopedia. Redirect page. Redirect to: Area under ...