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Cinnarizine's antagonistic effects of D2 dopamine receptors in the striatum leads to symptoms of depression, tremor, muscle rigidity, tardive dyskinesia, and akathisia. 17 of 100 new parkinsonism cases are linked to administration of either cinnarizine or flunarizine. [5] Drug induced parkinsonism is the second leading cause of parkinsonism. [22]
Treatment and management of addiction encompasses the range of approaches aimed at helping individuals overcome addiction, most commonly in the form of DSM-5 diagnosed substance use disorders, or behavioral addictions such as problematic gambling and social media addiction. Treatment is one of the recovery pathways that individuals can follow ...
The use of sedating drugs alongside hydroxyzine can cause oversedation and confusion if administered at high doses—any form of hydroxyzine treatment alongside sedatives should be done under the supervision of a doctor. [28] [25] Because of the potential for more severe side effects, this drug is on the list to avoid in the elderly. [29]
"Treatment of vertigo due to acute unilateral vestibular loss with a fixed combination of cinnarizine and dimenhydrinate: a double-blind, randomized, parallel-group clinical study". Clin Ther . 26 (6): 866– 77.
Amid public health warnings about rising stimulant use disorders, the Food and Drug Administration is urging drugmakers to develop treatments for cocaine and methamphetamine addiction.
Given Hazelden’s long history of treating addicts, Seppala could have stubbornly stuck to the brand. But he was willing to consider alternatives. He’d come to Hazelden in the mid-’70s, as its first adolescent resident, for an addiction to drugs and alcohol. “I blamed myself so much,” he recalled. “I really hated myself.
Some common side effects such as drowsiness, dry mouth, and tiredness may occur. Meclizine has been shown to have fewer dry mouth side effects than the traditional treatment for motion sickness, transdermal scopolamine. [16] A very serious allergic reaction to this drug is unlikely, but immediate medical attention should be sought if it occurs.
The drugs in this category have limited risk and addiction potential. Examples are naproxen and diclofenac in small amounts, cinnarizine , 400 mg ibuprofen up to 20 tablets and also 500 mg paracetamol up to 50 tablets.
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