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Itraconazole (400 mg/day) appears to have efficacy equal to that of fluconazole in the treatment of nonmeningeal infection and have the same relapse rate after therapy is discontinued. However, itraconazole seems to perform better in skeletal lesions, whereas fluconazole performs better in pulmonary and soft tissue infection.
Itraconazole was patented in 1978 and approved for medical use in the United States in 1992. [7] [8] It is on the World Health Organization's List of Essential Medicines. [9] Recent research works suggest itraconazole (ITZ) could also be used in the treatment of cancer by inhibiting the hedgehog pathway [10] in a similar way to sonidegib.
Fluconazole is the preferred medication for coccidioidal meningitis, due to its penetration into CSF. [3] Intrathecal or intraventricular amphotericin B therapy is used if infection persists after fluconazole treatment. [31] Itraconazole is used for cases that involve treatment of infected person's bones and joints.
But the truth is that toenail fungus or onychomycosis, to use the medical term, is incredibly common and can happen to anyone. In fact, 1 in 10 people are affected , and for those over 70, this ...
Little evidence supports probiotics for either prevention or treatment, even among those with frequent vaginal infections. [17] [18] For infections of the mouth, treatment with topical clotrimazole or nystatin is usually effective. [6] Oral or intravenous fluconazole, itraconazole, or amphotericin B may be used if these do not work. [6]
Onychomycosis (also known as "dermatophytic onychomycosis", or "tinea unguium" [2] is a fungal infection of the nail. [8] It is the most common disease of the nails and constitutes about half of all nail abnormalities. [9] This condition may affect toenails or fingernails, but toenail infections are particularly common. It occurs in about 10% ...
Mild onychomycosis sometimes responds to a combination of topical antifungal medication, sometimes applied as special medicinal nail lacquer, and periodic filing of the nail surface. For advanced onychomycosis, especially if more than one nail is infected, systemic medication (pills) is preferred. Home remedies are often used, although their ...
Onychomycosis Benzoxaborole antifungal is for the treatment of onychomycosis of toenails. It is applied to the affected toenail once daily for 48 weeks. The major adverse effects associated with its use is the ingrowing of toenails and application site reactions including exfoliation, erythema, and dermatitis.