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Rubidium-82 (82 Rb) is a radioactive isotope of rubidium. 82 Rb is widely used in myocardial perfusion imaging.This isotope undergoes rapid uptake by myocardiocytes, which makes it a valuable tool for identifying myocardial ischemia in Positron Emission Tomography (PET) imaging.
Cardiac PET (or cardiac positron emission tomography) is a form of diagnostic imaging in which the presence of heart disease is evaluated using a PET scanner. Intravenous injection of a radiotracer is performed as part of the scan. Commonly used radiotracers are Rubidium-82, Nitrogen-13 ammonia and Oxygen-15 water. [1]
Rubidium-82 chloride is a form of rubidium chloride containing a radioactive isotope of rubidium. It is marketed under the brand name Cardiogen-82 by Bracco Diagnostics for use in Myocardial perfusion imaging . [ 1 ]
Positron emission tomography (PET) [1] is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption.
Other than 87 Rb, the longest-lived radioisotopes are 83 Rb with a half-life of 86.2 days, 84 Rb with a half-life of 33.1 days, and 86 Rb with a half-life of 18.642 days. All other radioisotopes have half-lives less than a day. 82 Rb is used in some cardiac positron emission tomography scans to assess myocardial perfusion. It has a half-life of ...
The instantaneous wave-free ratio (iFR, sometimes referred to as the instant wave-free ratio or instant flow reserve) is a diagnostic tool used to assess whether a stenosis is causing a limitation of blood flow in coronary arteries with subsequent ischemia. iFR is performed during cardiac catheterisation (angiography) using invasive coronary pressure wires which are placed in the coronary ...
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Cardiac CT (CCT) is a modified form of the traditional chest CT due to the difficulty of imaging the complex, moving heart. [16] This is achieved through the use of thin slices and high-resolution scanning, as well as the addition of electrocardiogram (ECG) gating or triggering to capture a motion-free image.