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Pinta (also known as azul, carate, empeines, lota, mal del pinto, and tina) is a human skin disease caused by infection with the spirochete Treponema carateum, which is morphologically and serologically indistinguishable from the bacterium that causes syphilis and bejel.
Together with Stevens–Johnson syndrome (SJS) it forms a spectrum of disease, with TEN being more severe. [2] Early symptoms include fever and flu-like symptoms. [2] A few days later the skin begins to blister and peel forming painful raw areas. [2] Mucous membranes, such as the mouth, are also typically involved. [2]
Keratolytic Winter erythema (also known as Oudtshoorn disease [1] or Oudtshoorn skin [2] [3]) is a rare autosomal dominant skin disease of unknown cause which causes redness and peeling of the skin on the palms and soles. [4] Onset, increased prominence and severity usually occurs during winter. [5] [6] It is a type of genodermatosis. [7]
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
We will solicit skin disease pictures from Cochrane Skin consumers globally for addition to Cochrane Skin Systematic Reviews in the Cochrane Library and Wikipedia via the social media outreach. Pictures will need to be of acceptable quality as judged by our medical and technical experts and come with:
The rise of medetomidine comes as overdose deaths have fallen slightly. More than 107,000 people died of a drug overdose last year, down from about 111,000 in 2022, according to a recent report.
Medetomidine is a veterinary anesthetic drug with potent sedative effects and emerging illicit drug adulterant. [ 1 ] It is a racemic mixture of two stereoisomers , levomedetomidine and dexmedetomidine , the latter being the isomer with the pharmacologic effect as an alpha 2- adrenergic agonist .
Medetomidine, a powerful animal tranquilizer, has emerged as one of the latest substances found mixed with other common street drugs. The drug has recently been cited as the likely culprit behind ...