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The history of coronaviruses is an account of the discovery of the diseases caused by coronaviruses and the diseases they cause. It starts with the first report of a new type of upper-respiratory tract disease among chickens in North Dakota, U.S., in 1931.
But, unlike other viral infections, the incidence of polio – the rarer severe form of the infection – increased in the 20th century and reached a peak around 1952. The invention of a cell culture system for growing the virus enabled Jonas Salk (1914–1995) to make an effective polio vaccine. [53]
[21] [22] According to the World Health Organization, approximately 10 million new TB infections occur every year, and 1.5 million people die from it each year – making it the world's top infectious killer (before COVID-19 pandemic). [21] However, there is a lack of sources which describe major TB epidemics with definite time spans and death ...
The pandemic spread east to Indonesia by 1852, and China and Japan in 1854. The Philippines were infected in 1858 and Korea in 1859. In 1859, an outbreak in Bengal contributed to transmission of the disease by travelers and troops to Iran, Iraq, Arabia and Russia. [22] Japan suffered at least seven major outbreaks of cholera between 1858 and 1902.
On average a coronavirus particle has 74 surface spikes. [53] Each spike is about 20 nm long and is composed of a trimer of the S protein. The S protein is in turn composed of an S1 and S2 subunit. The homotrimeric S protein is a class I fusion protein which mediates the receptor binding and membrane fusion between the virus and host cell. The ...
11 1850–1899. 12 1900–1949. 13 1950–1999. ... Many early innovations of the Bronze Age were prompted by the increase in trade, and this also applies to the ...
The Lower Paleolithic period lasted over 3 million years, during which there many human-like species evolved including toward the end of this period, Homo sapiens.The original divergence between humans and chimpanzees occurred 13 (), however interbreeding continued until as recently as 4 Ma, with the first species clearly belonging to the human (and not chimpanzee) lineage being ...
The timeline of the COVID-19 pandemic lists the articles containing the chronology and epidemiology of SARS-CoV-2, [1] the virus that causes the coronavirus disease 2019 and is responsible for the COVID-19 pandemic. The first human cases of COVID-19 occurred in Wuhan, People's Republic of China, on or about 17 November 2019. [2]