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  2. Replication timing - Wikipedia

    en.wikipedia.org/wiki/Replication_timing

    The temporal order of replication of all the segments in the genome, called its replication-timing program, can now be easily measured in two different ways. [1] One way simply measures the amount of the different DNA sequences along the length of the chromosome per cell.

  3. Contact inhibition - Wikipedia

    en.wikipedia.org/wiki/Contact_inhibition

    Contact inhibition is a regulatory mechanism that functions to keep cells growing into a layer one cell thick (a monolayer). If a cell has plenty of available substrate space, it replicates rapidly and moves freely. This process continues until the cells occupy the entire substratum. At this point, normal cells will stop replicating.

  4. Eukaryotic DNA replication - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_DNA_replication

    Eukaryotic DNA replication. Eukaryotic DNA replication is a conserved mechanism that restricts DNA replication to once per cell cycle. Eukaryotic DNA replication of chromosomal DNA is central for the duplication of a cell and is necessary for the maintenance of the eukaryotic genome.

  5. Cell cycle withdrawal - Wikipedia

    en.wikipedia.org/wiki/Cell_cycle_withdrawal

    During the replication process, the DNA replication enzymes are not able to copy the ending sequences at the telomere. Those sequences, located at the end of the telomere and chromosome, would hence get lost gradually. Once all of these sequences have been worn out, the useful genetic information in the cell's chromosome would also get lost.

  6. Spindle checkpoint - Wikipedia

    en.wikipedia.org/wiki/Spindle_checkpoint

    Three types of cell division: binary fission (taking place in prokaryotes), mitosis and meiosis (taking place in eukaryotes).. When cells are ready to divide, because cell size is big enough or because they receive the appropriate stimulus, [20] they activate the mechanism to enter into the cell cycle, and they duplicate most organelles during S (synthesis) phase, including their centrosome.

  7. Chromosome segregation - Wikipedia

    en.wikipedia.org/wiki/Chromosome_segregation

    Chromosome segregation is the process in eukaryotes by which two sister chromatids formed as a consequence of DNA replication, or paired homologous chromosomes, separate from each other and migrate to opposite poles of the nucleus. This segregation process occurs during both mitosis and meiosis. Chromosome segregation also occurs in prokaryotes ...

  8. Mitosis - Wikipedia

    en.wikipedia.org/wiki/Mitosis

    The mitosis process in the cells of eukaryotic organisms follows a similar pattern, but with variations in three main details. "Closed" and "open" mitosis can be distinguished on the basis of nuclear envelope remaining intact or breaking down. An intermediate form with partial degradation of the nuclear envelope is called "semiopen" mitosis.

  9. Mitotic inhibitor - Wikipedia

    en.wikipedia.org/wiki/Mitotic_inhibitor

    This stops the cells during mitosis, while the chromosomes are still visible. Once the cells are centrifuged and placed in a hypotonic solution , they swell, spreading the chromosomes. After preparation, the chromosomes of the cells can be viewed under a microscope to have the banding patterns of the chromosomes examined.