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Fluorescence biomodulation is a form of photobiomodulation, which utilizes fluorescence energy to induce multiple transduction pathways that can modulate biological processes through the activation of photoacceptors found within many different cell and tissue types. According to Magalhães and Yoshimura, photoacceptors are molecules that do not ...
Photostimulation is the use of light to artificially activate biological compounds, cells, tissues, or even whole organisms. Photostimulation can be used to noninvasively probe various relationships between different biological processes, using only light.
LED therapy utilizes light-emitting diodes to deliver treatments based on mechanisms such as photodynamic Therapy (PDT) and photobiomodulation (PBMT). PDT targets and destroys diseased cells, while PBMT stimulates cellular repair and reduces inflammation .
Whereas high-power lasers are used in laser medicine to cut or destroy tissue, it is claimed that application of low-power lasers relieves pain or stimulates and enhances cell function. The effects appear to be limited to a specified set of wavelengths and new research has demonstrated effectiveness at myopia control. [ 6 ]
Photobiology is the scientific study of the beneficial and harmful interactions of light (technically, non-ionizing radiation) in living organisms. [1] The field includes the study of photophysics, photochemistry, photosynthesis, photomorphogenesis, visual processing, circadian rhythms, photomovement, bioluminescence, and ultraviolet radiation effects.
Optical scattering occurs due to mismatches in refractive index of the different tissue components, ranging from cell membranes to whole cells. Cell nuclei and mitochondria are the most important scatterers. [11] Their dimensions range from 100 nm to 6 μm, and thus fall within the NIR window.
Cells in vivo may be partially protected against the effects of photodynamic therapy by the presence of singlet oxygen scavengers (such as histidine). Certain skin cells are somewhat resistant to PDT in the absence of molecular oxygen; further supporting the proposal that the Type-II process is at the heart of photoinitiated cell death. [3]
Nasal aPDT addresses the issues of antibiotic-induced resistance in multiple ways. As a site-specific therapy, it does not interfere with the overall microbiome because it is not systemically administered. Moreover, phenothiazinium photosensitizers can target negatively charged bacterial cells leaving zwitterionic host tissues unharmed. [80]