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Chloropyridines are important intermediates to pharmaceuticals and agrochemicals. [1] A major use of 2-chloropyridine is the production of production of the fungicide pyrithione. Reaction of 4-chloropyridine with thioglycolic acid gives pyridylmercaptoacetic acid, a step in the production of cephalosporin antibiotics.
List of sulfonamides; Author of The Demon Under the Microscope, a history of the discovery of the sulfa drugs; A History of the Fight Against Tuberculosis in Canada (Chemotherapy) Presentation speech, Nobel Prize in Physiology and Medicine, 1939; The History of WW II Medicine "Five Medical Miracles of the Sulfa Drugs".
[3] [4] Herbal medicine in India is largely guided by folk medicine, both in codified cultural practices shared widely (Ayurveda, [5] Siddha, Unani), and highly localized practices unique to individual tribes or tribal groups . Between 3,000 [6] and 5,000 [7] species of medicinal plants grow in India with roughly 1,000 threatened with ...
Acylsulfonamide is a functional group in organic chemistry that is sometimes used in medicinal chemistry. [1] It consists of a sulfonamide group (SO 2 NH) linked to an acyl group (RCO), forming the structure R 1-CO-NH-SO 2-R 2. This moiety is found in several biologically active molecules and marketed drugs, serving as an useful pharmacophore. [2]
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The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.
The reaction of 3-bromo-4-chloropyridine with furan and lithium amalgam gives 1,4-epoxy-dihydroquinoline through the 2,3-pyridyne intermediate. The reaction of 4-bromopyridine with sodium in liquid ammonia gives both 3-aminopyridine and 4-aminopyridine through the 3,4-pyridyne intermediate and an E1cB-elimination reaction .
2-Chloropyridine is an aryl chloride with the formula C 5 H 4 ClN. It is a colorless liquid that is mainly used to generate fungicides and insecticides in industry. It also serves to generate antihistamines and antiarrythymics for pharmaceutical purposes. [2] It is one of three isomers of chloropyridine.