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Efficacy was evaluated in a single-arm cohort of an open-label, multicenter trial (SNDX-5613-0700, NCT04065399; AUGMENT-101) in 104 adult and pediatric participants (at least 30 days old) with relapsed or refractory (R/R) acute leukemia with a lysine methyltransferase 2A gene translocation. [3]
Levothyroxine is a synthetic form of thyroxine (T 4), which is secreted by the thyroid gland. Levothyroxine and thyroxine are chemically identical: natural thyroxine is also in the "levo" chiral form, the difference is only in terminological preference. T 4 is biosynthesized from tyrosine.
CJC-1295 may markedly increase plasma growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels in animals and humans. [1] [2] [3] [5] With a single injection, in human subjects, CJC-1295 DAC may increase plasma GH levels by 2- to 10-fold for 6 days or longer and plasma IGF-1 levels by 0.5- to 3-fold for 9 to 11 days. [3]
2.5–40 mg/day Depo-Provera: Progestogen: IM: 150 mg every 3 mos: Depo-SubQ Provera 104: Progestogen: SC: 104 mg every 3 mos Hydroxyprogesterone caproate: Proluton: Progestogen: IM: 250 mg/wk Dydrogesterone: Duphaston: Progestogen: Oral: 20 mg/day Drospirenone: Slynd: Progestogen: Oral: 3 mg/day Domperidone [d] Motilium: Prolactin releaser ...
Phytoestrogens are plant compounds that mimic estrogen when broken down in the body. Isoflavones are a type of phytoestrogen that comes from soybean products. This is a major category of menopause ...
1 mg guanfacine tablets. Guanfacine is FDA-approved as monotherapy or augmentation with stimulants to treat attention deficit hyperactivity disorder (ADHD). [3] [16] [17] Unlike stimulant medications, guanfacine is regarded as having no abuse potential, and may even be used to reduce abuse of drugs including nicotine and cocaine. [18]
scFv: single-chain variable fragment. di-scFv: dimeric single-chain variable fragment. sdAb: single-domain antibody. BsAb: bispecific monoclonal antibody: 3funct: trifunctional antibody. BiTE: bi-specific T-cell engager. This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been ...
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