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Creatine-alpha-ketoglutarate is a salt formed from alpha-ketoglutaric acid (AKG) and creatine. Creatine is a mass-produced fitness supplement that is supposed to increase the user's muscle mass, strength and power. Creatine requires a delivery system for cell uptake. [citation needed] An example is arginine alpha-ketoglutarate.
A 2009 systematic review discredited concerns that creatine supplementation could affect hydration status and heat tolerance and lead to muscle cramping and diarrhea. [ 69 ] [ 70 ] Despite weight gain due to water retention and potential cramps being two seemingly "common" side effects, new research indicates that these side effects are likely ...
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A 2018 review of over 900 adults found that those who engaged in regular physical activity had better sleep quality. A review of studies also found a connection between exercise and improved sleep ...
α-Ketoglutarate is a component of the citric acid cycle, a cyclical metabolic pathway located in the mitochondria.This cycle supplies the energy that cells need by sequentially metabolizing (indicated by →) citrate through seven intermediate metabolites and then converting the eighth intermediate metabolite, oxaloacetate, back to citrate: [2]
Extended or chronic sleep loss can lead to weight gain, ... A good night’s rest can also lower the risk of serious health problems, increase cognitive function, improve mood/mental health, and ...
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