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A colorectal polyp is a polyp (fleshy growth) occurring on the lining of the colon or rectum. [1] Untreated colorectal polyps can develop into colorectal cancer. [2] Colorectal polyps are often classified by their behaviour (i.e. benign vs. malignant) or cause (e.g. as a consequence of inflammatory bowel disease).
Traditional serrated adenoma seen under microscopy with H&E stain, showing serrated crypts. SPS may occur with one of two phenotypes: distal or proximal. [6] The distal phenotype may demonstrate numerous small polyps in the distal colon and rectum, whereas the proximal phenotype may be characterized by relatively fewer, but larger polyps in the proximal colon (cecum, ascending colon, etc.). [6]
The treatment of colorectal cancer can be aimed at cure or palliation. The decision on which aim to adopt depends on various factors, including the person's health and preferences, as well as the stage of the tumor. [140] Assessment in multidisciplinary teams is a critical part of determining whether the patient is suitable for surgery or not ...
A sessile serrated lesion (SSL) is a premalignant flat (or sessile) lesion of the colon, predominantly seen in the cecum and ascending colon. SSLs are thought to lead to colorectal cancer through the (alternate) serrated pathway. [1] [2] This differs from most colorectal cancer, which arises from mutations starting with inactivation of the APC ...
Virtual colonoscopy, also called computed tomography colonography (CTC) or CT colonography, is a noninvasive way to check for polyps and colon cancer tumors. If you need a colonoscopy, you may ...
The adenomatous polyp is considered pre-malignant, i.e., likely to develop into colon cancer. [14] The other types of polyps that can occur in the colon are hyperplastic and inflammatory polyps, which are unlikely to develop into colorectal cancer. [15] About 5% of people aged 60 will have at least one adenomatous polyp of 1 cm diameter or ...
Treatments for early-stage colon or colorectal cancer can include a polypectomy, or the removal of polyps during a colonoscopy, or endoscopic mucosal resection, which is the removal of larger ...
The incidence of the mutation is between 1 in 10,000 and 1 in 15,000 births. By age 35 years, 95% of individuals with FAP (>100 adenomas) have polyps. Without colectomy, colon cancer is virtually inevitable. The mean age of colon cancer in untreated individuals is 39 years (range 34–43 years). [13]
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