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Those with long-term problems are at risk of urinary tract infections. [1] Causes include blockage of the urethra, nerve problems, certain medications, and weak bladder muscles. [1] Blockage can be caused by benign prostatic hyperplasia (BPH), urethral strictures, bladder stones, a cystocele, constipation, or tumors. [1]
Rare (<0.1%) adverse effects include: Urinary retention; Prolonged QT interval; Torsades de Pointes; Ataxia; Breast enlargement or engorgement; Lactation; Cardiospasm
Overactive bladder is not life-threatening, [1] but most people with the condition have problems for years. [1] The cause of overactive bladder is unknown. [1] Risk factors include obesity, caffeine, and constipation. [5] Poorly controlled diabetes, poor functional mobility, and chronic pelvic pain may worsen the symptoms. [1]
Around one third of men will develop urinary tract (outflow) symptoms, of which the principal underlying cause is benign prostatic hyperplasia. [ 26 ] Once symptoms arise, their progress is variable and unpredictable with about one third of patients improving, one third remaining stable and one third deteriorating.
Bacillus Calmette-Guerin (BCG) is the standard immunotherapy drug for bladder cancer. Immunotherapy uses your own immune system to attack cancer cells. In this case, a catheter is used to insert ...
Those with long-term problems are at risk of urinary tract infections. [21] Causes include blockage of the urethra, nerve problems, certain medications, and weak bladder muscles. [21] Blockage can be caused by benign prostatic hyperplasia (BPH), urethral strictures, bladder stones, a cystocele, constipation, or tumors. [21]
Trospium chloride is a muscarinic antagonist used to treat overactive bladder. [3] It has side effects typical of this class of drugs, namely dry mouth, stomach upset, and constipation; these side effects cause problems with people taking their medicine as directed.
Alpha-adrenergic agonists may cause urinary retention by stimulating the contraction of the urethral sphincter. Calcium channel blockers may decrease the contractility of the smooth muscle tissue in the urinary bladder, causing urinary retention with overflow incontinence. Epidural anesthesia and delivery also can cause the overflow incontinence.
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