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Rhizopus microsporus causes rice seedling blight and is a severe crop disease in Asia. [15] In addition, R. microsporus significantly affects sunflower yield in terms of both (oil) quality and quantity. The free fatty acid content of sunflower oil increases from 0.8% to 19.4%.
Rhizoxin is biosynthesised by Paraburkholderia rhizoxinica, a bacterial endosymbiont of the fungus Rhizopus microsporus. [3] It is one of a large group of rhizoxin-like compounds produced by the bacteria. [4] The bacterial endosymbiont can be grown independently in culture.
Rhizopus is a genus of common saprophytic fungi on plants and specialized parasites on animals. They are found in a wide variety of organic substances, including "mature fruits and vegetables", [ 2 ] jellies, syrups, leather, bread, peanuts, and tobacco.
This includes people with illnesses such as HIV/AIDS, and people taking medicines such as steroids or cancer treatments. [14] People with diabetes also tend to develop fungal infections. [19] Very young and very old people, also, are groups at risk. [20] Individuals being treated with antibiotics are at higher risk of fungal infections. [21]
Bottom line: Most drugs carry a risk, but if you've been prescribed an oral or injected fluoroquinolone and you're concerned about side effects, be sure to talk to your doctor about switching.
Fungal-bacterial endosymbiosis encompasses the mutualistic relationship between a fungus and intracellular bacteria species residing within the fungus. Many examples of endosymbiotic relationships between bacteria and plants, algae and insects exist and have been well characterized, however fungal-bacteria endosymbiosis has been less well described.
Marbofloxacin is a carboxylic acid derivative third generation fluoroquinolone antibiotic. It is used in veterinary medicine under the brand names Marbocyl , Forcyl, Marbo vet and Zeniquin . A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available under the name Aurizon ( CAS number 115550-35-1).
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.