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The original antigenic sin: When the body first encounters an infection it produces effective antibodies against its dominant antigens and thus eliminates the infection. But when it encounters the same infection, at a later evolved stage, with a new dominant antigen, with the original antigen now being recessive, the immune system will still produce the former antibodies against this old "now ...
What is original antigenic sin or immunological imprinting? With new COVID variant-specific booster shots set to roll out in the coming week, vaccine scientists argue that more research is needed ...
original antigenic sin. Also called antigenic imprinting and the Hoskins effect. The tendency of the human body's immune system to preferentially utilize immunological memory of a previous infection when a second, slightly different version of the pathogen (e.g. a virus or bacterium) is encountered in subsequent infections. The success of ...
But these clones would consist of naive cells which are not allowed to proliferate by the weakly binding antibodies produced by the priorly stimulated clone. This doctrine is known as the original antigenic sin. [21] This phenomenon comes into play particularly in immune responses against influenza, dengue and HIV viruses. [25]
Original antigenic sin; Vaccine adverse event; Other ways in which antibodies can (unusually) make an infection worse instead of better Blocking antibody, which can be either good or bad, depending on circumstances; Hook effect, most relevant to in vitro tests but known to have some in vivo relevances
Through an immunological phenomenon, known as original antigenic sin, the immune system is not able to adequately respond to the stronger infection, and the secondary infection becomes far more serious. [6]
Depiction of the sin of Adam and Eve (The Garden of Eden with the Fall of Man by Jan Brueghel the Elder and Pieter Paul Rubens). Original sin (Latin: peccatum originale) in Christian theology refers to the condition of sinfulness that all humans share, which is inherited from Adam and Eve due to the Fall, involving the loss of original righteousness and the distortion of the Image of God. [1]
What Is ‘Dexter: Original Sin’ About? Seacia Pavao/SHOWTIME According to the official plot summary, the prequel follows Dexter “as he transitions from student to avenging serial killer.”