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Untreated PID can result in long-term complications including infertility, ectopic pregnancy, chronic pelvic pain, and cancer. [2] [3] [4] The disease is caused by bacteria that spread from the vagina and cervix. [5] It has been reported that infections by Neisseria gonorrhoeae or Chlamydia trachomatis are present in 75 to 90 percent of cases. [2]
The time from exposure to symptoms is usually between two and 14 days, with most symptoms appearing between four and six days after infection, if they appear at all. Both men and women with infections of the throat may experience a sore throat , though such infection does not produce symptoms in 90% of cases.
In men, those with a chlamydial infection show symptoms of infectious inflammation of the urethra in about 50% of cases. [15] Symptoms that may occur include: a painful or burning sensation when urinating, an unusual discharge from the penis, testicular pain or swelling, or fever.
Though strep throat can be treated with antibiotics, untreated infections can turn dangerous quickly. An iGAS infection can cause many different complications, some of which can be life-threatening.
In up to a third of cases, the underlying strep infection may not have caused any symptoms. [citation needed] The rate of development of rheumatic fever in individuals with untreated strep infection is estimated to be 3%. The incidence of recurrence with a subsequent untreated infection is substantially greater (about 50%). [60]
Most infections show no symptoms, in which case it is known as latent tuberculosis. [1] Around 10% of latent infections progress to active disease that, if left untreated, kill about half of those affected. [1] Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. [1]
Vaginal infections left untreated can lead to further complications, especially for the pregnant woman. For bacterial vaginosis, these include "premature delivery, postpartum infections, clinically apparent and subclinical pelvic inflammatory disease , [as well as] postsurgical complications (after abortion, hysterectomy, caesarian section ...
Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. [4] [7]This initial stage of sepsis is followed by suppression of the immune system. [8]