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Drug-induced pigmentation of the skin may occur as a consequence of drug administration, and the mechanism may be postinflammatory hyperpigmentation in some cases, but frequently is related to actual deposition of the offending drug in the skin. [2]: 125–6 The incidence of this change varies, and depends on the type of medication involved.
A painful and itchy reddish/purple patch of skin that occurs in the same location with repeated exposures to the causative drug is the classic presentation of a fixed drug reaction. The lips, genitals, and hands are often involved.
Maceration of the skin is common with AC—meaning the skin can soften and lighten in color, Dr. Batra says. If the skin gets too irritated, it can break apart and bleed. Other symptoms include:
Other behaviors of long-term methamphetamine users that may cause or accelerate the symptoms of meth mouth are the failure to pay attention to oral hygiene and excessive food intake during binges, especially sugary foods; [5] [6] the drug's users often report strong cravings for sugar and consume large amounts of high-sugar beverages. The ...
Counterintuitively, constant licking of the lips causes drying and irritation, and eventually the mucosa splits or cracks. [2] The lips have a greater tendency to dry out in cold, dry weather. [citation needed] Digestive enzymes present in the saliva may also irritate the lips, and the evaporation of the water in saliva saps moisture from them. [8]
Smoker melanosis in a patient consuming 2 packs of cigarette per day. Smoking or the use of nicotine-containing drugs is the cause to Smoker's melanosis. [10] [11] Tar-components (benzopyrenes) are also known to stimulate melanocytes to melanin production, and other unknown toxic agents in tobacco may also be the cause.
Maculopapular rash (MPR) is a less-well defined and benign form of drug-induced adverse skin reactions; while not classified in the SCARs group, it shares a similar pathophysiology with SCARs and is caused by some of the same drugs which cause SCARs. [2] Adverse drug reactions are major therapeutic problems estimated to afflict up to 20% of ...
Bradycardia; Hypertension (high blood pressure); Allergic reactions (e.g. dyspnoea (shortness of breath), bronchospasm, wheezing, angioneurotic oedema) Anaphylaxis; Changes in appetite