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Carnitine palmitoyltransferase II (CPT II) is a peripheral inner mitochondrial membrane protein ubiquitously found as a monomeric protein in all tissues that oxidize fatty acids. [12] It catalyzes the transesterification of palmitoylcarnitine back into palmitoyl-CoA which is now an activated substrate for β-oxidation inside the matrix.
CPT2 together with carnitine palmitoyltransferase I oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders and carnitine palmitoyltransferase II deficiency. [6] Acyl-CoA from cytosol to the mitochondrial matrix
Carnitine palmitoyltransferase I deficiency; Carnitine palmitoyltransferase II deficiency; Medium-chain acyl-coenzyme A dehydrogenase deficiency; Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency; Very long-chain acyl-coenzyme A dehydrogenase deficiency
Numerous genetic disorders are caused by errors in fatty acid metabolism.These disorders may be described as fatty oxidation disorders or as a lipid storage disorders, and are any one of several inborn errors of metabolism that result from enzyme defects affecting the ability of the body to oxidize fatty acids in order to produce energy within muscles, liver, and other cell types.
Carnitine palmitoyltransferase II, an important metabolic enzyme. Carnitine palmitoyltransferase II deficiency, a condition that prevents the body from converting certain fats into energy; Killarney Airport, CPT2 ICAO airport code, located in Killarney, Ontario, Canada
21% of Americans have chronic pain. A new study found that diets rich in vegetables, fruits, grains, lean proteins, and dairy was linked to less chronic pain.
Collins also suffers from drop-foot, Nic revealed, a condition the Mayo Clinic describes as "difficulty lifting the front part of the foot." "In one of his feet, he has like no sensation, which is ...
Carnitine O-palmitoyltransferase (also called carnitine palmitoyltransferase) is a mitochondrial transferase enzyme (EC 2.3.1.21) involved in the metabolism of palmitoylcarnitine into palmitoyl-CoA. A related transferase is carnitine acyltransferase .