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  2. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    A cell is said to be homozygous for a particular gene when identical alleles of the gene are present on both homologous chromosomes. [2] An individual that is homozygous-dominant for a particular trait carries two copies of the allele that codes for the dominant trait. This allele, often called the "dominant allele", is normally represented by ...

  3. Homologous chromosome - Wikipedia

    en.wikipedia.org/wiki/Homologous_chromosome

    Homologous chromosomes can repair this damage by aligning themselves with chromosomes of the same genetic sequence. [16] Once the base pairs have been matched and oriented correctly between the two strands, the homologous chromosomes perform a process that is very similar to recombination, or crossing over as seen in meiosis.

  4. Locus (genetics) - Wikipedia

    en.wikipedia.org/wiki/Locus_(genetics)

    Diploid and polyploid cells whose chromosomes have the same allele at a given locus are called homozygous with respect to that locus, while those that have different alleles at a given locus are called heterozygous. [3] The ordered list of loci known for a particular genome is called a gene map.

  5. Glossary of genetics and evolutionary biology - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_genetics_and...

    Contrast homozygous. homoallele A mutant allele having a different mutation at the same site as another allele. Intragenic recombination between homoalleles cannot produce a functional cistron. [8] homologous chromosomes. Also homologs or homologues.

  6. Loss of heterozygosity - Wikipedia

    en.wikipedia.org/wiki/Loss_of_heterozygosity

    A diploid population of 10 individuals, that bottlenecked down to three individuals repeatedly, resulted in all individuals homozygous. In genetics, loss of heterozygosity (LOH) is a type of genetic abnormality in diploid organisms in which one copy of an entire gene and its surrounding chromosomal region are lost. [1]

  7. Bivalent (genetics) - Wikipedia

    en.wikipedia.org/wiki/Bivalent_(genetics)

    The search for the homologous target, helped by numerous proteins collectively referred as the synaptonemal complex, cause the two homologs to pair, between the leptotene and the pachytene phases of meiosis I. [4] Resolution of the DNA recombination intermediate into a crossover exchanges DNA segments between the two homologous chromosomes at a ...

  8. Homologous recombination - Wikipedia

    en.wikipedia.org/wiki/Homologous_recombination

    Homologous recombination is a type of genetic recombination in which genetic information is exchanged between two similar or identical molecules of double-stranded or single-stranded nucleic acids (usually DNA as in cellular organisms but may be also RNA in viruses).

  9. Gene knockout - Wikipedia

    en.wikipedia.org/wiki/Gene_knockout

    Homologous recombination is the exchange of genes between two DNA strands that include extensive regions of base sequences that are identical to one another. In eukaryotic species, bacteria, and some viruses, homologous recombination happens spontaneously and is a useful tool in genetic engineering.