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The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA. Homozygous describes a genotype consisting of two identical alleles at a given locus, heterozygous describes a genotype consisting of two different alleles at a locus, hemizygous describes a genotype consisting of only a single copy of a particular gene in an ...
Figure 1: Inheritance pattern of dominant (red) and recessive (white) phenotypes when each parent (1) is homozygous for either the dominant or recessive trait. All members of the F 1 generation are heterozygous and share the same dominant phenotype (2), while the F 2 generation exhibits a 6:2 ratio of dominant to recessive phenotypes (3).
MNS antibodies display dosage (they react stronger against cells which are homozygous vs heterozygous for the antigen in question). Anti-M and anti-N antibodies are naturally occurring, cold-reacting IgM-class antibodies. [7] Anti-M and anti-N are generally clinically insignificant.
In medical genetics, compound heterozygosity is the condition of having two or more heterogeneous recessive alleles at a particular locus that can cause genetic disease in a heterozygous state; that is, an organism is a compound heterozygote when it has two recessive alleles for the same gene, but with those two alleles being different from each other (for example, both alleles might be ...
The phenotype of a homozygous dominant pair is 'A', or dominant, while the opposite is true for homozygous recessive. Heterozygous pairs always have a dominant phenotype. [11] To a lesser degree, hemizygosity [12] and nullizygosity [13] can also be seen in gene pairs.
Under the law of dominance in genetics, an individual expressing a dominant phenotype could contain either two copies of the dominant allele (homozygous dominant) or one copy of each dominant and recessive allele (heterozygous dominant). [1] By performing a test cross, one can determine whether the individual is heterozygous or homozygous ...
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By comparing the differential amount of hybridization of the target DNA to each of these redundant probes, it is possible to determine specific homozygous and heterozygous alleles. [1] Although oligonucleotide microarrays have a comparatively lower specificity and sensitivity, the scale of SNPs that can be interrogated is a major benefit.