Search results
Results from the WOW.Com Content Network
Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B 3). [2] Symptoms include inflamed skin , diarrhea , dementia , and sores in the mouth. [ 1 ] Areas of the skin exposed to friction and radiation are typically affected first. [ 1 ]
Pellagra, a similar condition, is also caused by low nicotinamide; this disorder results in dermatitis, diarrhea, and dementia. [citation needed] Hartnup disease is a disorder of amino acid transport in the intestine and kidneys; otherwise, the intestine and kidneys function normally, and the effects of the disease occur mainly in the brain and ...
A disease that was characterized by dermatitis of sunlight-exposed skin was described in Spain in 1735 by Gaspar Casal. He attributed the cause to poor diet. [52] In northern Italy it was named pellagra from the Lombard language (agra = holly-like or serum-like; pell = skin). [53] [54] In time, the disease was more closely linked specifically ...
Grace Arabell Goldsmith (8 April 1904 – 28 April 1975) was a U.S. physician best known for her research on nutritional deficiency diseases, B-complex vitamins, and the vitamin enrichment of foods. She identified the cause of the disease pellagra .
Deficiency causes pellagra, a reversible nutritional wasting disease characterized by four classic symptoms often referred to as the four Ds: diarrhea, dermatitis, dementia, and death. The dermatitis occurs on areas of skin exposed to sunlight, such as backs of hands and neck.
The Casal collar or Casal necklace is a medical sign in which there is a redness and darkening of the skin around the neck, seen in people with pellagra. [2] It becomes prominent following exposure to sun, and can be itchy with a burning feeling and pain. [1] It can blister and weep, and turn into thick dark skin, with a coppery hue. [1]
Some physicians at the time believed that the disease arose in consequence of bad genes, airborne germs, or miasma resulting from poor sanitary conditions. [6] Goldberger's theory that pellagra was associated with diet contradicted the most widely accepted medical opinion that pellagra was an infectious disease.
Pellagra, a condition caused by niacin (vitamin B3) deficiency, may cause a thick greyish fur to develop on the dorsal tongue, along with other oral signs. [9] Transient surface discoloration of the tongue and other soft tissues in the mouth can occur in the absence of hairy tongue.