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Bronchoscopic lung volume reduction (BLVR) is a procedure to reduce the volume of air within the lungs. BLVR was initially developed in the early 2000s [ 1 ] [ 2 ] as a minimally invasive treatment for severe COPD that is primarily caused by emphysema .
In obstructive lung disease, the FEV1 is reduced due to an obstruction of air escaping from the lungs. Thus, the FEV1/FVC ratio will be reduced. [4] More specifically, according to the National Institute for Clinical Excellence, the diagnosis of COPD is made when the FEV 1 /FVC ratio is less than 0.7 or [8] the FEV 1 is less than 75% of predicted; [9] however, other authoritative bodies have ...
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...
COPD is defined as a forced expiratory volume in 1 second divided by the forced vital capacity (FEV1/FVC) that is less than 0.7 (or 70%). [8] The residual volume, the volume of air left in the lungs following full expiration, is often increased in COPD, as is the total lung capacity, while the vital capacity remains relatively normal.
Lung volume reduction may be offered to those with advanced emphysema. When other treatments fail, and the emphysema is in the upper lobes, a surgical option may be possible. [ 49 ] A number of minimally invasive bronchoscopic procedures are increasingly used to reduce lung volume.
The presence of interlobar collateral ventilation will affect the choice of lung volume reduction procedure that may be offered in severe cases of emphysema. Emphysema usually develops in later years from the breakdown of alveolar walls resulting in much larger airspaces and much larger pathways for a preferential route of collateral ventilation.
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