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Oxalobacter formigenes is a Gram negative oxalate-degrading anaerobic bacterium that was first isolated from the gastrointestinal tract of a sheep in 1985. [1] To date, the bacterium has been found to colonize the large intestines of numerous vertebrates, including humans, and has even been isolated from freshwater sediment. [2]
The glyoxylate cycle is a variant of the citric acid cycle. [4] It is an anabolic pathway occurring in plants and bacteria utilizing the enzymes isocitrate lyase and malate synthase. Some intermediate steps of the cycle are slightly different from the citric acid cycle; nevertheless oxaloacetate has the same function in both processes. [1]
Oxalate also forms coordination compounds where it is sometimes abbreviated as ox. It is commonly encountered as a bidentate ligand. When the oxalate chelates to a single metal center, it always adopts the planar conformation. As a bidentate ligand, it forms a 5-membered MC 2 O 2 ring. An illustrative complex is potassium ferrioxalate, K 3 [Fe ...
Oxalobacter is a genus of Gram-negative bacteria in the Oxalobacteraceae family. The species are chemoorganotrophs and strictly anaerobic. [1] They are found in rumens of animals such as cattle and in feces of other animals, rodents, and humans.
Oxalate oxidase （Enzyme Commission number EC 1.2.3.4 [2] ）occurs mainly in plants. It can degrade oxalic acid into carbon dioxide and hydrogen peroxide. [3]Oxalate decarboxylase (OXDC，EC 4.1.1.2) is a kind of oxalate degrading enzyme containing Mn 2+, [4] found mainly in fungi or some bacteria.
After the development of kidney failure patients may get deposits of oxalate in the bones, joints and bone marrow. Severe cases may develop haematological problems such as anaemia and thrombocytopaenia. The deposition of oxalate in the body is sometimes called "oxalosis" to be distinguished from "oxaluria" which refers to oxalate in the urine.
Oxalobacter vibrioformis is an oxalate-degrading anaerobic bacterium that was isolated from anoxic freshwater sediments. [1] O. vibrioformis is a Gram-negative, non-spore-forming, motile, vibrioid rod which belongs to the genus Oxalobacter. O. vibrioformis uses oxalate and oxamate as its sole source of energy and acetate as its main source of ...
In enzymology, an oxalate decarboxylase (EC 4.1.1.2) is an oxalate degrading enzyme that catalyzes the chemical reaction oxalate + H + ⇌ {\displaystyle \rightleftharpoons } formate + CO 2 Thus, the two substrates of this enzyme are oxalate and H + , whereas its two products are formate and CO 2 .