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  2. Insulin-like growth factor 1 - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor_1

    Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD), is an autosomal recessive disorder characterized by a lack of insulin-like growth factor 1 (IGF-1; somatomedin-C) production in response to growth hormone (GH; hGH; somatotropin). [32]

  3. Insulin-like growth factor 1 receptor - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor...

    The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by a hormone called insulin-like growth factor 1 and by a related hormone called IGF-2. It belongs to the large class of tyrosine kinase receptors. This receptor mediates the effects of IGF-1 ...

  4. Laron syndrome - Wikipedia

    en.wikipedia.org/wiki/Laron_syndrome

    Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD), is an autosomal recessive disorder characterized by a lack of insulin-like growth factor 1 (IGF-1; somatomedin-C) production in response to growth hormone (GH; hGH; somatotropin). [6]

  5. List of causes of hypoglycemia - Wikipedia

    en.wikipedia.org/wiki/List_of_causes_of_hypoglycemia

    Insulin; Insulin-like growth factor; Insulin receptor antibodies; Insulinoma; Intrauterine growth retardation; Jamaican vomiting sickness; Ketotic hypoglycemia of infancy; Kidney Failure; Lanreotide; Laron dwarfism; Leucine-induced hypoglycaemia; Levomepromazine; Liver cancer; Liver glycogen synthase deficiency; Long-chain hydroxyacyl-CoA ...

  6. Insulin-like growth factor - Wikipedia

    en.wikipedia.org/wiki/Insulin-like_growth_factor

    The IGF-1 receptor is the "physiological" receptor. IGF-1 binds to it at significantly higher affinity than it binds the insulin receptor. Like the insulin receptor, the IGF-1 receptor is a receptor tyrosine kinase—meaning the receptor signals by causing the addition of a phosphate molecule on particular tyrosines. The IGF-2 receptor only ...

  7. Insulin Resistance: From Symptoms to Treatment - AOL

    www.aol.com/insulin-resistance-symptoms...

    Insulin resistance, or low insulin sensitivity, happens when cells throughout the body don’t respond properly to the hormone insulin, especially cells in muscles, fat and the liver. Insulin is a ...

  8. Insulin receptor - Wikipedia

    en.wikipedia.org/wiki/Insulin_receptor

    The insulin receptor (IR) is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of receptor tyrosine kinase. [5] Metabolically, the insulin receptor plays a key role in the regulation of glucose homeostasis; a functional process that under degenerate conditions may result in a range of clinical manifestations including diabetes and cancer.

  9. Congenital iodine deficiency syndrome - Wikipedia

    en.wikipedia.org/wiki/Congenital_iodine...

    Dwarfism may also be caused by malnutrition or other hormonal deficiencies, such as insufficient growth hormone secretion, hypopituitarism, decreased secretion of growth hormone-releasing hormone, deficient growth hormone receptor activity and downstream causes, such as insulin-like growth factor 1 (IGF-1) deficiency. [14]

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