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Styrene is regarded as a "known carcinogen", especially in case of eye contact, but also in case of skin contact, of ingestion and of inhalation, according to several sources. [20] [33] [34] [35] Styrene is largely metabolized into styrene oxide in humans, resulting from oxidation by cytochrome P450.
Exposure to styrene can damage organs, inflame lungs and make it hard to breathe, according to previous Enquirer reporting of a 2005 styrene leak incident in Cincinnati's East End.
General-purpose polystyrene is clear, hard, and brittle. It is an inexpensive resin per unit weight. It is a poor barrier to air and water vapor and has a relatively low melting point. [6] Polystyrene is one of the most widely used plastics, with the scale of its production being several million tonnes per year. [7]
Studies indicate that humans ingest significant amounts of microplastics daily through food, especially seafood [5] and inhalation, with estimates ranging from 39,000 to 52,000 particles per person annually [6] Additionally, the presence of microplastics in human feces suggests widespread exposure and absorption. [7]
Here's what the Drug & Poison Information Center at Cincinnati Children’s Hospital advises regarding returning home following the styrene leak.
Just before 4 p.m., Tuesday, around a half-dozen people were at the Whitewater Township Community Center, where residents have been encouraged to take shelter while an evacuation order remains active.
Styrene oxide is a main metabolite of styrene in humans or animals, resulting from oxidation by cytochrome P450. It is considered possibly carcinogenic from gavaging significant amounts into mice and rats. [4] Styrene oxide is subsequently hydrolyzed in vivo to styrene glycol by epoxide hydrolase. [5]
“That’s nearly 17,000 people dying from prescription opiate overdoses every year. And more than 400,000 go to an emergency room for that reason.” Clinics that dispensed painkillers proliferated with only the loosest of safeguards, until a recent coordinated federal-state crackdown crushed many of the so-called “pill mills.”