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  2. Confocal endoscopy - Wikipedia

    en.wikipedia.org/wiki/Confocal_endoscopy

    Confocal endoscopy, or confocal laser endomicroscopy (CLE), is a modern imaging technique that allows the examination of real-time microscopic and histological features inside the body. In the word "endomicroscopy", endo- means "within" and -skopein means "to view or observe".

  3. Endomicroscopy - Wikipedia

    en.wikipedia.org/wiki/Endomicroscopy

    Endomicroscopy is a technique for obtaining histology-like images from inside the human body in real-time, [1] [2] [3] a process known as ‘optical biopsy’. [4] [5] It generally refers to fluorescence confocal microscopy, although multi-photon microscopy and optical coherence tomography have also been adapted for endoscopic use.

  4. Scanning laser ophthalmoscopy - Wikipedia

    en.wikipedia.org/wiki/Scanning_laser_ophthalmoscopy

    Scanning laser ophthalmoscopy developed as a method to view a distinct layer of the living eye at the microscopic level. The use of confocal methods to diminish extra light by focusing detected light through a small pinhole made possible the imaging of individual layers of the retina with greater distinction than ever before. [4]

  5. Confocal microscopy - Wikipedia

    en.wikipedia.org/wiki/Confocal_microscopy

    Fluorescence and confocal microscopes operating principle. Confocal microscopy, most frequently confocal laser scanning microscopy (CLSM) or laser scanning confocal microscopy (LSCM), is an optical imaging technique for increasing optical resolution and contrast of a micrograph by means of using a spatial pinhole to block out-of-focus light in image formation. [1]

  6. McCrone Research Institute - Wikipedia

    en.wikipedia.org/wiki/McCrone_Research_Institute

    The McCrone Research Institute is a not-for-profit educational and research organization for microscopy located in Chicago, Illinois. [1] It was founded by Dr. Walter C. McCrone in 1960. [ 2 ] With more than 30,000 enrollments since its incorporation, it is the largest private, independent, nonprofit microscopy and microanalysis institution in ...

  7. Fluorescence-lifetime imaging microscopy - Wikipedia

    en.wikipedia.org/wiki/Fluorescence-lifetime...

    Fluorescence-lifetime imaging microscopy or FLIM is an imaging technique based on the differences in the exponential decay rate of the photon emission of a fluorophore from a sample. It can be used as an imaging technique in confocal microscopy , two-photon excitation microscopy , and multiphoton tomography.

  8. Optical sectioning - Wikipedia

    en.wikipedia.org/wiki/Optical_sectioning

    With no modification to the microscope, i.e. with a simple wide field light microscope, the quality of optical sectioning is governed by the same physics as the depth of field effect in photography. For a high numerical aperture lens, equivalent to a wide aperture, the depth of field is small (shallow focus) and gives good optical sectioning.

  9. Scanning confocal electron microscopy - Wikipedia

    en.wikipedia.org/wiki/Scanning_confocal_electron...

    Scanning confocal electron microscopy (SCEM) is an electron microscopy technique analogous to scanning confocal optical microscopy (SCOM). In this technique, the studied sample is illuminated by a focussed electron beam, as in other scanning microscopy techniques, such as scanning transmission electron microscopy or scanning electron microscopy .

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