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  2. Inbreeding - Wikipedia

    en.wikipedia.org/wiki/Inbreeding

    Inbreeding coefficients of various populations in Europe and Asia. Offspring of biologically related persons are subject to the possible effects of inbreeding, such as congenital birth defects. The chances of such disorders are increased when the biological parents are more closely related.

  3. Harlequin-type ichthyosis - Wikipedia

    en.wikipedia.org/wiki/Harlequin-type_ichthyosis

    The diagnosis of harlequin-type ichthyosis relies on both physical examination and laboratory tests. Physical assessment at birth is vital for the initial diagnosis of harlequin ichthyosis. Physical examination reveals characteristic symptoms of the condition, especially the abnormalities in the skin surface of newborns.

  4. Birth defect - Wikipedia

    en.wikipedia.org/wiki/Birth_defect

    Another study on 21 European hazardous-waste sites showed that those living within 3 km had an increased risk of giving birth to infants with birth defects and that as distance from the land increased, the risk decreased. These birth defects included neural tube defects, malformations of the cardiac septa, anomalies of arteries and veins, and ...

  5. Assessment of suicide risk - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_suicide_risk

    Suicide risk assessment is a process of estimating the likelihood for a person to attempt or die by suicide. The goal of a thorough risk assessment is to learn about the circumstances of an individual person with regard to suicide, including warning signs, risk factors, and protective factors. [ 1 ]

  6. Developmental toxicity - Wikipedia

    en.wikipedia.org/wiki/Developmental_toxicity

    It is considered to be one of the main targets of developmental toxicity and defects in neurulation is a common consequence of toxicant exposure and results in large proportion of human defects. [9] Neurulation exposure to developmental toxicity is caused by the increased rate of cell proliferation and the ventral to dorsal migration of ...

  7. Genetic purging - Wikipedia

    en.wikipedia.org/wiki/Genetic_purging

    Genetic purging is the increased pressure of natural selection against deleterious alleles prompted by inbreeding. [1]Purging occurs because deleterious alleles tend to be recessive, which means that they only express all their harmful effects when they are present in the two copies of the individual (i.e., in homozygosis).

  8. Consanguine marriage - Wikipedia

    en.wikipedia.org/wiki/Consanguine_marriage

    Multiple studies have established consanguinity as a high cause for birth defects and abnormalities. A risk of autosomal recessive disorders increases in offspring coming from consanguineous marriages due to the increased likelihood of receiving recessive genes from cognate parents. [2] According to population based case-control studies, a ...

  9. Birth defects of diethylstilbestrol - Wikipedia

    en.wikipedia.org/wiki/Birth_defects_of...

    The NCI study provides limited evidence of an increased risk of birth defects in the sons or daughters of women who were exposed prenatally to DES. An increased risk of ovarian cancer in the daughters of women exposed in utero was observed, but it was based on three cases of almost 800, so the finding is considered preliminary and requires ...