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2. H2 receptor antagonist - Wikipedia

   en.wikipedia.org/wiki/H2_receptor_antagonist

   Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.

3. Drugs for acid-related disorders - Wikipedia

   en.wikipedia.org/wiki/Drugs_for_acid-related...

   The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.

4. Category:H2 receptor antagonists - Wikipedia

   en.wikipedia.org/wiki/Category:H2_receptor...

   Pages in category "H2 receptor antagonists" The following 20 pages are in this category, out of 20 total. This list may not reflect recent changes. ...

5. Cimetidine - Wikipedia

   en.wikipedia.org/wiki/Cimetidine

   Cimetidine, sold under the brand name Tagamet among others, is a histamine H 2 receptor antagonist that inhibits stomach acid production. [1] [9] [10] It is mainly used in the treatment of heartburn and peptic ulcers.

6. Proton-pump inhibitor - Wikipedia

   en.wikipedia.org/wiki/Proton-pump_inhibitor

   [citation needed] Because the H,K-ATPase is the final step of acid secretion, an inhibitor of this enzyme is more effective than receptor antagonists in suppressing gastric acid secretion. [75] All of these drugs inhibit the gastric H,K-ATPase by covalent binding, so the duration of their effect is longer than expected from their levels in the ...

7. Histamine receptor - Wikipedia

   en.wikipedia.org/wiki/Histamine_receptor

   H 2 receptor H2 Receptors: Found mainly in the stomach lining (parietal cells), H2 receptors regulate gastric acid secretion by stimulating the production of hydrochloric acid. H2 antagonists (H2 blockers) are used to reduce stomach acid production and treat conditions like gastroesophageal reflux disease (GERD) and peptic ulcers. [3]