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Transitional cell carcinoma is a type of cancer that arises from the transitional epithelium, a tissue lining the inner surface of these hollow organs. [1] It typically occurs in the urothelium of the urinary system ; in that case, it is also called urothelial carcinoma .
Invasive urothelial carcinoma is a type of transitional cell carcinoma. It is a type of cancer that develops in the urinary system: the kidney , urinary bladder , and accessory organs. Transitional cell carcinoma is the most common type of bladder cancer and cancer of the ureter , urethra , renal pelvis , the ureters , the bladder , and parts ...
The most common histology seen in primary urethral cancer (a cancer which originates in the urethra, as opposed to cancer cells from elsewhere in the body which metastasize to the area) is urothelium, a type of transitional epithelium. Urothelial cell cancers comprise just over half of primary urethral cancers.
Transitional cell carcinoma can metastasize, or spread to other parts of the body via the surrounding tissues, the lymph system, and the bloodstream. It can spread to the tissues and fat surrounding the kidney, the fat surrounding the ureter, or, more progressively, lymph nodes and other organs, including bone.
Bladder tumors are classified by their appearance under the microscope, and by their cell type of origin. Over 90% of bladder tumors arise from the cells that form the bladder's inner lining, called urothelial cells or transitional cells; the tumor is then classified as urothelial cancer or transitional cell cancer.
Urachal cancer is a very rare type of cancer arising from the urachus or its remnants. [1] The disease might arise from metaplastic glandular epithelium or embryonic epithelial remnants originating from the cloaca region. [2] It occurs in roughly about one person per 1 million people per year varying on the geographical region. [3]
When gastric cancer is caught early, the five year survival rate is estimated to be around 90%. [ 4 ] [ 5 ] However when diagnosed at an advanced stage, survival falls to less than 30%. Colorectal cancer has demonstrated an increasing incidence in younger populations with the US lifetime risk estimated to be about 4%. [ 6 ]
Carcinoma is a malignancy that develops from epithelial cells. [1] Specifically, a carcinoma is a cancer that begins in a tissue that lines the inner or outer surfaces of the body, and that arises from cells originating in the endodermal, mesodermal [2] or ectodermal germ layer during embryogenesis.