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Apolipoprotein A-V is a protein that in humans is encoded by the APOA5 gene on chromosome 11. [5] [6] [7] It is significantly expressed in liver. [8]The protein encoded by this gene is an apolipoprotein and an important determinant of plasma triglyceride levels, a major risk factor for coronary artery disease.
Acute promyelocytic leukemia represents 10–12% of AML cases. [16] The median age is approximately 30–40 years, [33] which is considerably younger than the other subtypes of AML (70 years), however in elderly population APL has peculiar characteristics. [34] Incidence is higher among individuals of Latin American or South European origin. [35]
Acute monocytic leukemia (AMoL, or AML-M5) [2] is a type of acute myeloid leukemia. In AML-M5 >80% of the leukemic cells are of monocytic lineage. [3] This cancer is characterized by a dominance of monocytes in the bone marrow. There is an overproduction of monocytes that the body does not need in the periphery.
Acute myelomonocytic leukemia (AMML) is a form of acute myeloid leukemia that involves a proliferation of CFU-GM myeloblasts and monoblasts.AMML occurs with a rapid increase amount in white blood cell count and is defined by more than 20% of myeloblast in the bone marrow.
In the United States between 2011 and 2016, the median survival of a person with AML was 8.5 months, with the 5 year survival being 24%. [11] This declines with age, with the poorer prognosis being associated with an age greater than 65 years, and the poorest prognosis seen in those aged 75–84.
"The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials" (PDF). Blood. 98 (6): 1752– 1759.
EY chief economist Greg Daco estimated US GDP would contract by 1.5% in 2025 and 2.1% in 2026 if the tariffs kick in, as they would "dampen" consumer spending and business investment. Inflation ...
A A&TWF – Acquisition and technology work force a – Army AA – Assembly area AA – Anti-aircraft AA – Aegis ashore AAA – Anti-aircraft artillery "Triple A" AAAV – Advanced Amphibious Assault Vehicle AAC – Army Air Corps AAD – Armored amphibious dozer AADC – Area air defense commander AAE – Army acquisition executive AAG – Anti-aircraft gun AAK – Appliqué armor kit (US ...