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  2. Alpha-1 blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_blocker

    Alpha-1 blocker, blocks alpha receptors and it relaxes the smooth muscles in the bladder. It helps the urine to flow smoothly and it can lessen the pain caused by the bladder pressing on the prostate. [44] [45] Selective alpha-1 blockers are better tolerated than non-selective alpha blockers in the body and therefore works better on BPH. [2]

  3. Adrenergic blocking agent - Wikipedia

    en.wikipedia.org/wiki/Adrenergic_blocking_agent

    Non-selective alpha blocker: Paroxysmal hypertension, pheochromocytoma-induced sweating [24] Dibenzyline [25] Phentolamine: Non-selective alpha blocker: Reversal agent for unnecessary prolonged local analgesia [26] Regitine [27] Prazosin: Selective alpha-1 blocker: Hypertension, benign prostatic hyperplasia, PTSD associated nightmares and ...

  4. Alpha blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha_blocker

    When the term "alpha blocker" is used without further qualification, it can refer to an α 1 blocker, an α 2 blocker, a nonselective blocker (both α 1 and α 2 activity), or an α blocker with some β activity. [2] However, the most common type of alpha blocker is usually an α 1 blocker. Non-selective α-adrenergic receptor antagonists include:

  5. Phenoxybenzamine - Wikipedia

    en.wikipedia.org/wiki/Phenoxybenzamine

    Clinically, non-selective alpha antagonists block alpha receptors (but do not differentiate between alpha-1 and alpha-2). They are used as antihypertensives because they block alpha-receptor-mediated vasoconstriction. The block on alpha-2 receptors further potentiates beta-effects, increasing cardiac output.

  6. Benign prostatic hyperplasia - Wikipedia

    en.wikipedia.org/wiki/Benign_prostatic_hyperplasia

    The older, less selective α1-adrenergic blocker prazosin is not a first-line choice for either high blood pressure or prostatic hyperplasia; it is a choice for patients who present with both problems at the same time. The older, broadly non-selective alpha-blocker medications such as phenoxybenzamine are not recommended for control of BPH. [74]

  7. Prazosin - Wikipedia

    en.wikipedia.org/wiki/Prazosin

    Prazosin is an α 1-blocker that acts as a non-selective inverse agonist at α 1-adrenergic receptors, including of the α 1A-, α 1B-, and α 1D-adrenergic receptor subtypes. [24] It binds to these receptors with affinity (K i ) values of 0.13 to 1.0 nM for the α 1Α -adrenergic receptor, 0.06 to 0.62 nM for the α 1B -adrenergic receptor ...

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