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Pseudobulbar affect (PBA), or emotional incontinence, is a type of neurological disorder characterized by uncontrollable episodes of crying or laughing. PBA occurs secondary to a neurologic disorder or brain injury. Patients may find themselves crying uncontrollably at something that is only slightly sad, being unable to stop themselves for ...
Avanir Pharmaceuticals (NAS: AVNR) is a biotechnology company developing therapies focused on the central nervous system. ... Nuedexta, for the treatment of pseudobulbar affect. Skip to main ...
Since pseudobulbar palsy is a syndrome associated with other diseases, treating the underlying disease may eventually reduce the symptoms of pseudobulbar palsy. [ citation needed ] Possible pharmacological interventions for pseudobulbar affect include the tricyclic antidepressants , serotonin reuptake inhibitors , and a novel approach utilizing ...
Emotional disturbance (e.g. pseudobulbar affect) and cognitive and behavioural changes (e.g. problems in word fluency, decision-making, and memory) are also seen. [ 2 ] [ 6 ] There can be lower motor neuron findings (e.g. muscle wasting, muscle twitching), upper motor neuron findings (e.g. brisk reflexes, Babinski reflex , Hoffman's reflex ...
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DXM/quinidine is used in the treatment of PBA. In a 12-week randomized, double-blind trial, amyotrophic lateral sclerosis and multiple sclerosis patients with significant PBA were given either Nuedexta 20/10 mg or placebo.
The growth continues for biopharmaceutical company Avanir Pharmaceuticals , which reported its 10th consecutive quarter of double-digit revenue growth despite widening losses for the quarter. For ...
Emotional lability is seen or reported in various conditions including borderline personality disorder, [3] histrionic personality disorder, [4] post-traumatic stress disorder, [5] hypomanic or manic episodes of bipolar disorder, [6] and neurological disorders or brain injury (where it is termed pseudobulbar affect), such as after a stroke. [7]