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Tail flick test apparatus. The tail flick test is a test of the pain response in animals, similar to the hot plate test. It is used in basic pain research and to measure the effectiveness of analgesics, by observing the reaction to heat. It was first described by D'Amour and Smith in 1941. [1]
In 1937, the South African Railways (SAR) placed one 3 ft 6 in (1,067 mm) Cape gauge 2-10-4 Class 21 steam locomotive in service, designed for mixed traffic and suitable for light rail. It was designed by A.G. Watson, chief mechanical engineer of the SAR from 1929 to 1936, and built by the North British Locomotive Company in Glasgow.
Bessemer and Lake Erie Railroad No. 643 is the sole survivor of the class H-1 2-10-4 "Texas type" steam locomotives built by the Baldwin Locomotive Works in 1944 for the Bessemer and Lake Erie Railroad, primarily used for hauling heavy mainline freight trains in Pennsylvania and Ohio, until retirement in 1952.
Example of a traditional set-up for the tail flick assay. The tail flick assay or tail flick test uses a high-intensity beam of light aimed at a rodent's tail to detect nociception. [1] In normal rodents, the noxious heat sensation induced by the beam of light causes a prototypical movement of the tail via the flexor withdrawal reflex. [2]
Santa Fe No. 5000 is a 2-10-4 "Texas" type steam locomotive constructed by Baldwin Locomotive Works in 1930 for the Atchison, Topeka and Santa Fe Railway. No. 5000 was immediately nicknamed the "Madame Queen" [2] and remained a unique member of its own class. It was donated to the City of Amarillo, Texas in 1957. As of 2023, Santa Fe 5000 is ...
Santa Fe 5017 is a 2-10-4 or "Texas" type steam locomotive built by the Baldwin Locomotive Works in 1944 for the Atchison, Topeka and Santa Fe Railway. History
In 1930, the C&O ordered the first of forty 2-10-4 "Texas"-types from Lima, which they classified as the T-1 class, and they shared identical design features with the Erie’s 2-8-4s. [ 1 ] The T-1s were equipped with a trailing truck booster that exerted 15,275 pounds-force (67.95 kN) of tractive effort.
Numbers 5011 to 5035, when built, were the largest and fastest class of "Texas"-type locomotives ever built and equipped with Timken roller bearings on every axle.. The engines had a maximum output of 5,600 horsepower (4,200 kW) measured at the rear of the tender, at a top speed of 70 miles per hour (110 km/h).