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[9] [94] Autoimmune disease may cause abnormalities in embryos, which in turn may lead to miscarriage. As an example, coeliac disease increases the risk of miscarriage by an odds ratio of approximately 1.4. [43] [44] A disruption in normal immune function can lead to the formation of antiphospholipid antibody syndrome.
Beta-thalassemia (β-thalassemia) is an autosomal dominant blood condition that results in the reduction of hemoglobin production. The cause for the disorder is related to a genetic mutation of the HBB gene. This gene is responsible for providing the instructions to produce beta-globin; one of the major components of hemoglobin.
Recurrent miscarriage in itself is associated with later development of coronary artery disease with an odds ratio of approximately 2, [50] increased risk of ovarian cancer, [51] increased risk of cardiovascular complications, [52] and an increased risk of all-cause mortality of 44%, 86%, and 150% for women with a history of 1, 2, or 3 ...
It can cause life-threatening clots in the body and complications during pregnancy. What you need to know about factor V Leiden - a blood clotting condition that can cause miscarriages Skip to ...
Miscarriage risks are those circumstances, conditions, and substances that increase the risk of miscarriage. Some risks are modifiable and can be changed. Other risks cannot be modified and can't be changed. Risks can be firmly tied to miscarriages and others are still under investigation.
Recurring miscarriage may increase the incidence of intrusive thoughts in women and their partners. [5] Miscarriage has an emotional effect and can also lead to psychological disorders. One disorder that can develop is primary maternal preoccupation. This psychological trauma can develop as a response to early pregnancy loss.
Elevated blood lead levels can increase risk of preeclampsia and miscarriage and can lead to birth defects. [ 14 ] [ 15 ] Lead is believed to predominantly affect male reproduction by the disruption of hormones, which reduces the quantity of sperm production in the seminiferous tubules .
Fetal warfarin syndrome is a disorder of the embryo which occurs in a child whose mother took the medication warfarin (brand name: Coumadin) during pregnancy.Resulting abnormalities include low birth weight, slower growth, intellectual disability, deafness, small head size, and malformed bones, cartilage, and joints.