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  2. Erythrocyte fragility - Wikipedia

    en.wikipedia.org/wiki/Erythrocyte_fragility

    Erythrocyte fragility refers to the propensity of erythrocytes (red blood cells, RBC) to hemolyse (rupture) under stress. It can be thought of as the degree or proportion of hemolysis that occurs when a sample of red blood cells are subjected to stress (typically physical stress, and most commonly osmotic and/or mechanical stress).

  3. Laboratory specimen - Wikipedia

    en.wikipedia.org/wiki/Laboratory_specimen

    Variety of microbiological samples. A laboratory specimen is sometimes a biological specimen of a medical patient's tissue, fluids, or other samples used for laboratory analysis to assist in differential diagnosis or staging of a disease process. These specimens are often the most reliable method of diagnosis, depending on the ailment.

  4. Hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_anemia

    Extravascular hemolysis refers to hemolysis taking place in the liver, spleen, bone marrow, and lymph nodes. [30] In this case little hemoglobin escapes into blood plasma . [ 32 ] The macrophages of the reticuloendothelial system in these organs engulf and destroy structurally-defective red blood cells, or those with antibodies attached, and ...

  5. Sample size determination - Wikipedia

    en.wikipedia.org/wiki/Sample_size_determination

    Sample size determination or estimation is the act of choosing the number of observations or replicates to include in a statistical sample. The sample size is an important feature of any empirical study in which the goal is to make inferences about a population from a sample.

  6. Hemolysis - Wikipedia

    en.wikipedia.org/wiki/Hemolysis

    A red blood cell in a hypotonic solution, causing water to move into the cell A red blood cell in a hypertonic solution, causing water to move out of the cell. Hemolysis or haemolysis (/ h iː ˈ m ɒ l ɪ s ɪ s /), [1] also known by several other names, is the rupturing of red blood cells (erythrocytes) and the release of their contents into surrounding fluid (e.g. blood plasma).

  7. Hemoglobinuria - Wikipedia

    en.wikipedia.org/wiki/Hemoglobinuria

    Hemoglobinuria is a condition in which the oxygen transport protein hemoglobin is found in abnormally high concentrations in the urine. [1] The condition is caused by excessive intravascular hemolysis, in which large numbers of red blood cells (RBCs) are destroyed, thereby releasing free hemoglobin into the plasma. [2]

  8. Hemolytic jaundice - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_jaundice

    Hemolysis secondary to drug toxicity [15] Thalassemia minor [16] Congenital dyserythropoietic anemia [17] The above list is not exhaustive, and rare causes of hemolysis such as Bartonella infection, [18] hemolysis due to transfusion reactions, [19] and microangiopathic hemolytic anemia [20] should be suspected when symptoms specific to those ...

  9. Intravascular hemolysis - Wikipedia

    en.wikipedia.org/wiki/Intravascular_hemolysis

    In the end, if the plasma concentration of the "free met-hemoglobin" and/or "free hemoglobin" is still too high for proximal tubule to absorb back into the body, then hemoglobinuria occurs, [3] indicating an extensive intravascular hemolysis. [3] These remaining free hemoglobin entities also begin to consume nitric oxide, which is critical ...