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Emergency 130 milligrams potassium iodide doses provide 100 mg iodide (the other 30 mg is the potassium in the compound), [17] which is roughly 700 times larger than the normal nutritional need (see recommended dietary allowance) for iodine, which is 150 micrograms (0.15 mg) of iodine (as iodide) per day for an adult.
Potassium iodide (KI) and potassium iodate ... If a person consumes a dose of one of these chemical compounds, his or her thyroid may saturate with stable iodine, ...
Other sources state that pure potassium iodide solution in water was eventually used for most of the thyroid protection after this accident. [26] There is "strong scientific evidence" for potassium iodide thyroid protection to help prevent thyroid cancer. Potassium iodide does not provide immediate protection but can be a component of a general ...
[14] [15] Potassium iodide (KI) is typically used for this purpose. [16] However, unjustified self-medicated preventive administration of stable KI is not recommended in order to avoid disturbing the normal thyroid function. Such a treatment must be carefully dosed and requires an appropriate KI amount prescribed by a specialised physician.
Similarly to potassium iodide (KI), sufficient consumption of tetraglycine hydroperiodide tablets may protect the thyroid against uptake of radioactive iodine. A 1995 study found that daily consumption of water treated with 4 tablets containing tetraglycine hydroperiodide reduced the uptake of radioactive iodine in human subjects to a mean of 1 ...
Four inorganic compounds are used as iodide sources, depending on the producer: potassium iodate, potassium iodide, sodium iodate, and sodium iodide. Any of these compounds supplies the body with the iodine required for the biosynthesis of thyroxine (T 4) and triiodothyronine (T 3) hormones by the thyroid gland.
Iodide transport is a key step in the biosynthesis of the thyroid hormones T4 and T3. [5] [6] For example, potassium perchlorate competitively inhibits the active iodide transport mechanism in the thyroid gland, which has the capacity to selectively concentrate iodide against a large concentration gradient. [5] [6]
Thyroid hormone synthesis, with the oxidation step labeled at center-left. PTU inhibits the enzyme thyroperoxidase, which normally acts in thyroid hormone synthesis by oxidizing the anion iodide (I −) to iodine (I 0), facilitating iodine's addition to tyrosine residues on the hormone precursor thyroglobulin.
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