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In 1834, German chemist Friedlieb Ferdinand Runge discovered a phenol, also known as carbolic acid, which he derived in an impure form from coal tar.In August 1865, Joseph Lister applied a piece of lint dipped in carbolic acid solution to the wound of an eleven-year-old boy at Glasgow Royal Infirmary, who had sustained a compound fracture after a cart wheel had passed over his leg.
The term creosote has a broad range of definitions depending on the origin of the coal tar oil and end-use of the material. With respect to wood preservatives, the United States Environmental Protection Agency (EPA) considers the term creosote to mean a pesticide for use as a wood preservative meeting the American Wood Protection Association (AWPA) Standards P1/P13 and P2. [6]
Phenol (also known as carbolic acid, phenolic acid, or benzenol) is an aromatic organic compound with the molecular formula C 6 H 5 OH. [5] It is a white crystalline solid that is volatile . The molecule consists of a phenyl group ( −C 6 H 5 ) bonded to a hydroxy group ( −OH ).
The antiseptic properties of phenol discovered by Jules Lemaire were put to good use by the British surgeon Joseph Lister (1827–1912), pioneer of the antiseptic method in operative surgery, who had the idea of putting all his surgical tools and gowns in carbolic acid, as well as the wounds of the operated, thus reducing the postoperative mortality rate from 40% to 15%.
Lifebuoy was originally, and for much of its history, a carbolic soap containing phenol (carbolic acid, a compound extracted from coal tar). The soaps manufactured today under the Lifebuoy brand do not contain phenol. Currently, there are many varieties of Lifebuoy.
The residue remaining in the autoclave vessel is a dark, syrupy mass called creosote, which is composed mainly of phenolic acid and cresylic acid. The original composition of creolin is a creosote tar oil, caustic soda, soaps, and very little water. It is of low technology and a very powerful disinfectant. [1]
The hospital had been free of infection but within days there were twelve cases of infection and four deaths. [55] In his notebook, Lister stated that the disease was a form of surgical fever, and particularly noted that recent surgical patients were infected the worst, but that those with older surgeries with suppurating wounds, 'mostly ...
Coal tar creosote; Wood creosote; Reduction product of vanillin using zinc powder in strong hydrochloric acid (Clemmensen reduction) Found as glycosides in green vanilla beans [2] It is also found in tequila. [3]