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However, pentamidine is suspected to work through various methods of interference of critical functions in DNA, RNA, phospholipid and protein synthesis. [ 8 ] [ 18 ] Pentamidine binds to adenine - thymine -rich regions of the Trypanosoma parasite DNA, forming a cross-link between two adenines four to five base pairs apart.
Sleeping sickness, or trypanosomiasis, is treated with pentamidine or suramin (depending on subspecies of parasite) delivered by intramuscular injection in the first phase of the disease, and with melarsoprol and eflornithine intravenous injection in the second phase of the disease.
Protists were once considered protozoans, but of late the categorization of unicellar organisms has undergone rapid development, however in literature, including scientific, there tends to persist the usage of the term antiprotozoal when they really mean anti-protist.
What is The Pink Stuff and how does it work? Made mostly of baking soda, quartz, and soap, The Pink Stuff works as a mild abrasive that gently wears away stuck-on stains. The tiny quartz particles ...
Omega-3 supplements are usually used by doctors to help manage high cholesterol, which is a more common issue as you get older, says Clifford Segil, DO, a neurologist at Providence Saint John’s ...
Move over, Wordle, Connections and Mini Crossword—there's a new NYT word game in town! The New York Times' recent game, "Strands," is becoming more and more popular as another daily activity ...
Glutaraldehyde is an organic compound with the formula (CH 2) 3 (CHO) 2.The molecule consists of a five carbon chain doubly terminated with formyl (CHO) groups. It is usually used as a solution in water, and such solutions exists as a collection of hydrates, cyclic derivatives, and condensation products, several of which interconvert.
Researchers compared how three antioxidants affected gray hair outcomes in mice: hesperetin, diosmetin, and luteolin, and found that one helped mitigate hair graying.
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