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  2. Mouse embryonic fibroblast - Wikipedia

    en.wikipedia.org/wiki/Mouse_embryonic_fibroblast

    Mouse Embryonic Fibroblasts (MEFs) are a type of fibroblast prepared from mouse embryo. MEFs show a spindle shape when cultured in vitro, a typical feature of fibroblasts. The MEF is a limited cell line. After several transmissions, MEFs will senesce and finally die off.

  3. 3T3 cells - Wikipedia

    en.wikipedia.org/wiki/3T3_cells

    The primary mouse embryonic fibroblast cells were transferred (the "T") every 3 days (the first "3"), and inoculated at the rigid density of 3 × 10 5 cells per 20 cm 2 dish (the second "3") continuously. [2] The spontaneously immortalized cells with stable growth rate were established after 20 to 30 generations in culture, and then named '3T3 ...

  4. FGF15 - Wikipedia

    en.wikipedia.org/wiki/FGF15

    FGF15 is found in the absorptive cells of the mouse ileum and plays an important role in feedback inhibition of hepatic bile acid synthesis. [8] FGF15 (and FGF19 in humans) function as hormones produced in response to bile acid absorption acting on the farnesoid X receptor FXR, are secreted into the portal venous circulation and bind onto the liver membrane receptor FGFR4/β-Klotho and repress ...

  5. Fibroblast - Wikipedia

    en.wikipedia.org/wiki/Fibroblast

    A fibroblast is a type of biological cell typically with a spindle shape [1] that synthesizes the extracellular matrix and collagen, [2] produces the structural framework for animal tissues, and plays a critical role in wound healing. [3]

  6. KLRG1 - Wikipedia

    en.wikipedia.org/wiki/KLRG1

    They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [9]

  7. Fibroblast growth factor 21 - Wikipedia

    en.wikipedia.org/wiki/Fibroblast_growth_factor_21

    Mice lacking FGF21 fail to fully induce PGC-1α expression in response to a prolonged fast and have impaired gluconeogenesis and ketogenesis. [26] FGF21 stimulates phosphorylation of fibroblast growth factor receptor substrate 2 and ERK1/2 in the liver. Acute FGF21 treatment induced hepatic expression of key regulators of gluconeogenesis, lipid ...

  8. Fibroblast activation protein, alpha - Wikipedia

    en.wikipedia.org/wiki/Fibroblast_activation...

    14089 Ensembl ENSG00000078098 ENSMUSG00000000392 UniProt Q12884 P97321 RefSeq (mRNA) NM_001291807 NM_004460 NM_007986 RefSeq (protein) NP_001278736 NP_004451 NP_032012 Location (UCSC) Chr 2: 162.17 – 162.25 Mb Chr 2: 62.33 – 62.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Fibroblast activation protein alpha (FAP-alpha) also known as prolyl endopeptidase FAP is an enzyme that ...

  9. Minute virus of mice - Wikipedia

    en.wikipedia.org/wiki/Minute_virus_of_mice

    Minute virus of mice (MVM) is the exemplar virus of the species Rodent protoparvovirus 1, in the genus Protoparvovirus [1] of the Parvoviridae family of viruses. [2] MVM exists in multiple variant forms including MVMp, which is the prototype strain that infects cells of fibroblast origin, while MVMi, the immunosuppressive strain, infects T lymphocytes. [3]

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