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Choline–containing phospholipids and other substances, like glycerophosphocholines, are transported in blood lipoproteins. Blood plasma choline levels in healthy fasting adults is 7–20 micromoles per liter (μmol/L) and 10 μmol/L on average. Levels are regulated, but choline intake and deficiency alters these levels.
The main complication resulting from pseudocholinesterase deficiency is the possibility of respiratory failure secondary to succinylcholine or mivacurium-induced neuromuscular paralysis. Individuals with pseudocholinesterase deficiency also may be at increased risk of toxic reactions, including sudden cardiac death, associated with recreational ...
In general, the word "choline" describes the various quaternary ammonium salts containing the N,N,N-trimethylethanolammonium cation. Found in most animal tissues, choline is a primary component of the neurotransmitter acetylcholine and functions with inositol as a basic constituent of lecithin. Choline also prevents fat deposits in the liver ...
News research suggests that consuming a moderate amount of choline through foods such as eggs, cabbage, and shiitake mushrooms could help reduce the risk of atherosclerotic heart disease.
In the case of long-term total-parenteral-nutrition-induced fatty liver disease, choline has been shown to alleviate symptoms. [ 36 ] [ 37 ] [ 38 ] This may be due to a deficiency in the methionine cycle .
[35] [36] Choline deficiency can lead to the development of MASLD. [37] Higher consumption of processed, red, and organ meats have been associated with higher risk of developing MASLD. [38] [39] [40] Some research also suggests eggs are also associated with developing MASLD.
Pseudocholinesterase deficiency may also affect local anaesthetic selection in dental procedures. The enzyme plays an important role in the metabolism of ester-based local anaesthetics, a deficiency lowers the margin of safety and increases the risk of systemic effects with this type of anaesthetic.
Here are the top nine signs of vitamin K deficiency. Read on to discover the 10 ways your body is trying to tell you you’re low on key vitamins. Amy Gorin is a freelance writer, ...