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It is caused by excess growth hormone (GH) after the growth plates have closed. The initial symptom is typically enlargement of the hands and feet. [3] There may also be an enlargement of the forehead, jaw, and nose. Other symptoms may include joint pain, thicker skin, deepening of the voice, headaches, and problems with vision. [3]
In older patients, emotional instability may be less evident, or depression may occur, and the symptoms and signs are manifestly circulatory. In many, the thyroid is not readily palpable. [4] Symptoms such as rapid heart rate, shortness of breath on exertion, and edema may predominate. Older patients also tend to have more weight loss and less ...
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Skin tags are benign growths that appear frequently on the neck, eyelids, groin, or armpits. Unlike a mole, which is pigmented, or a wart, which is round and rough to the touch, a skin tag looks ...
Wrinkly skin syndrome (WSS) is a rare genetic condition characterized by sagging, wrinkled skin, low skin elasticity, and delayed fontanelle (soft spot) closure, along with a range of other symptoms. [1] The disorder exhibits an autosomal recessive inheritance pattern with mutations in the ATP6V0A2 gene, leading to abnormal glycosylation events ...
[3] [4] [5] The underlying mechanism involves the abnormal growth of connective tissue, which is believed to be the result of the immune system attacking healthy tissues. [6] Diagnosis is based on symptoms, supported by a skin biopsy or blood tests. [6] While no cure is known, treatment may improve symptoms. [2]
A corn (or clavus, plural clavi) is a cone-shaped callus that penetrates into the dermis, usually on the feet or hands. Corns may form due to chronic pressure or rubbing at a pressure point (in this skin over a bone), or due to scar tissue from a healing wound creating pressure in a weight-bearing area such as the sole of the foot.
Sweating: Excessive sweating can create a moist environment that promotes bacterial growth. Friction: Wearing tight hats or helmets can cause friction, irritating the hair follicles and causing bumps.