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Arterial stiffness occurs as a consequence of biological aging, arteriosclerosis and genetic disorders, such as Marfan, Williams, and Ehlers-Danlos syndromes. [1] Inflammation plays a major role in arteriosclerosis and arterial stiffness. [ 2 ]
Compliance diminishes with age and menopause. Arterial compliance is measured by ultrasound as a pressure (carotid artery) and volume (outflow into aorta) relationship. [5] Compliance, in simple terms, is the degree to which a container experiences pressure or force without disruption. It is used as an indication of arterial stiffness.
The theory of the velocity of the transmission of the pulse through the circulation dates back to 1808 with the work of Thomas Young. [9] The relationship between pulse wave velocity (PWV) and arterial wall stiffness can be derived from Newton's second law of motion (=) applied to a small fluid element, where the force on the element equals the product of density (the mass per unit volume ...
The high pulse pressure in elderly people with hypertension or isolated systolic hypertension is explained by increased arterial stiffness, which typically accompanies aging and may be exacerbated by high blood pressure. [81] Many mechanisms have been proposed to account for the rise in peripheral resistance in hypertension.
The stiffness of the aorta is associated with a number of diseases and pathologies, and noninvasive measures of the pulse wave velocity are an independent indicator of hypertension. Measuring the pulse wave velocity (invasively and non-invasively) is a means of determining arterial stiffness .
A simple view of the hemodynamics of systemic arterial pressure is based around mean arterial pressure (MAP) and pulse pressure. Most influences on blood pressure can be understood in terms of their effect on cardiac output, [77] systemic vascular resistance, or arterial stiffness (the inverse of arterial compliance). Cardiac output is the ...
The doctors and nurses didn’t believe Tomisa Starr was having trouble breathing. Two years ago, Starr, 61, of Sacramento, California, was in the hospital for a spike in her blood pressure.
Pulse pressure is calculated as the difference between the systolic blood pressure and the diastolic blood pressure. [3] [4]The systemic pulse pressure is approximately proportional to stroke volume, or the amount of blood ejected from the left ventricle during systole (pump action) and inversely proportional to the compliance (similar to elasticity) of the aorta.