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In epidemiology, a non-pharmaceutical intervention (NPI) is any method used to reduce the spread of an epidemic disease without requiring pharmaceutical drug treatments. Examples of non-pharmaceutical interventions that reduce the spread of infectious diseases include wearing a face mask and staying away from sick people .
Epidemiological (and other observational) studies typically highlight associations between exposures and outcomes, rather than causation. While some consider this a limitation of observational research, epidemiological models of causation (e.g. Bradford Hill criteria) [7] contend that an entire body of evidence is needed before determining if an association is truly causal. [8]
Many theoretical studies of the population dynamics, structure and evolution of infectious diseases of plants and animals, including humans, are concerned with this problem. [27] Research topics include: antigenic shift; epidemiological networks; evolution and spread of resistance; immuno-epidemiology; intra-host dynamics; Pandemic; pathogen ...
Geoffrey Rose was born in London on 19 April 1926 to Arthur Norman Rose, a Methodist minister, and Mary née Wadsworth, who was the daughter of a Methodist minister. [2] In 1958 he joined the epidemiology department of the London School of Hygiene and Tropical Medicine (LSHTM) and became a part-time Reader in 1964.
A quasi-experiment is an empirical study used to estimate the causal impact of an intervention. Quasi-experiments shares similarities with experiments or randomized controlled trials, but specifically lack random assignment to treatment or control. Instead, quasi-experimental designs typically allow assignment to treatment condition to proceed ...
Randomized controlled trial [5]. Blind trial [6]; Non-blind trial [7]; Adaptive clinical trial [8]. Platform Trials; Nonrandomized trial (quasi-experiment) [9]. Interrupted time series design [10] (measures on a sample or a series of samples from the same population are obtained several times before and after a manipulated event or a naturally occurring event) - considered a type of quasi ...
Opponents argued for many years that this type of study cannot prove causation, but the eventual results of cohort studies confirmed the causal link which the case–control studies suggested, [12] [13] and it is now accepted that tobacco smoking is the cause of about 87% of all lung cancer mortality in the US.
Cohort studies represent one of the fundamental designs of epidemiology which are used in research in the fields of medicine, pharmacy, nursing, psychology, social science, and in any field reliant on 'difficult to reach' answers that are based on evidence . In medicine for instance, while clinical trials are used primarily for assessing the ...
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