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These small regions of high intensity are observed on T2 weighted MRI images (typically created using 3D FLAIR) within cerebral white matter (white matter lesions, white matter hyperintensities or WMH) [1] [2] or subcortical gray matter (gray matter hyperintensities or GMH). The volume and frequency is strongly associated with increasing age. [2]
T2*-weighted imaging of the brain 26 weeks after subarachnoid hemorrhage, showing hemosiderin deposits as hypointense areas. [1] T 2 *-weighted imaging is an MRI sequence to quantify observable or effective T 2 (T2* or "T2-star"). In this sequence, hemorrhages and hemosiderin deposits become hypointense. [2]
T2-weighted images also displaying cerebrospinal fluid and rarefied/cystic white matter. To view the remaining tissue, and get perspective on the damage done (also helpful in determining the rate of deterioration) (T1-weighted), proton density, and FLAIR images are ideal as they show radiating stripe patterns in the degenerating white matter.
MRI findings, including pencillike hyperintensities on T2-weighted sagittal images and "owl's eyes" or "snake eyes" sign on T2 axial images, indicate the infarction is predominately in the watershed area of the gray matter of ventral horn (anterior spinal artery infarct). [10]
Radiation-induced lumbar plexopathy (RILP) or radiation-induced lumbosacral plexopathy (RILSP) is nerve damage in the pelvis and lower spine area caused by therapeutic radiation treatments. RILP is a rare side effect of external beam radiation therapy [ 1 ] [ 2 ] [ 3 ] and both interstitial and intracavity brachytherapy radiation implants.
Posterior reversible encephalopathy syndrome; Other names: Reversible posterior leukoencephalopathy syndrome (RPLS) Posterior reversible encephalopathy syndrome visible on magnetic resonance imaging as multiple cortico-subcortical areas of T2-weighted hyperintense (white) signal involving the occipital and parietal lobes bilaterally and pons.
Diffuse hyperintensity on T2-weighted imaging, and hypointensity on T1-weighted imaging of the spinal cord can be an indication of the onset or progression of myelomalacia Treatment [ edit ]
T2 weighted: T2: Measuring spin–spin relaxation by using long TR and TE times Higher signal for more water content [1] Low signal for fat in standard Spine Echo (SE), [1] though not with Fast Spin Echo/Turbo Spin Echo (FSE/TSE). FSE/TSE is the standard of care in modern medicine because it is faster