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Phytoprogestogens, also known as phytoprogestins, are phytochemicals (that is, naturally occurring, plant-derived chemicals) with progestogenic effects. [1] [2]Relative to their phytoestrogen counterparts, phytoprogestogens are rare. [1]
It has been hypothesized that plants use a phytoestrogen as part of their natural defense against the overpopulation of herbivore animals by controlling female fertility. [ 3 ] [ 4 ] The similarities, at molecular level, of an estrogen and a phytoestrogen allow them to mildly mimic and sometimes act as an antagonist of estrogen. [ 2 ]
In vitro studies have shown genistein to induce apoptosis of testicular cells at certain levels, thus raising concerns about effects it could have on male fertility; [57] however, one study found that isoflavones had "no observable effect on endocrine measurements, testicular volume or semen parameters over the study period." in healthy males ...
Lack of progesterone causes irregular or painful, heavy menses: Oral progesterone is no more effective than placebo at alleviating symptoms of premenstrual syndrome: Progesterone can counteract stress, increase metabolism and decrease abdominal fat There is no evidence to support weight loss due to progesterone
The routine use of DHEA-S and other androgens is discouraged in the treatment of women with low androgen levels due to hypopituitarism, adrenal insufficiency, menopause due to ovarian surgery, glucocorticoid use, or other conditions associated with low androgen levels; this is because there are limited data supporting improvement in signs and ...
The main biological role of progestogens in the body is in the female reproductive system, and the male reproductive system, [19] with involvement in regulation of the menstrual cycle, maintenance of pregnancy, and preparation of the mammary glands for lactation and breastfeeding following parturition in women; in men progesterone affects ...
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